Distinguish between the genomic and nongenomic actions of steroid hormones. Which mechanism of action would be inhibited by a drug that interfered with protein synthesis? Explain.
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Distinguish between the genomic and nongenomic actions of steroid hormones. Which mechanism of action would be inhibited by a drug that interfered with protein synthesis? Explain.
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- 1) Why are steroid hormones unable to be stored in secretory vesicles? 2) Other than increasing hormone solubility, describe two other consequences of hormones binding to binding proteins.Trace in a stepwise manner the signaling pathway that involves a g-protein receptor leading to the release of intracellular calcium. Specify what class of hormones would be involved in this pathway.List the major categories of hormones on the basis of their chemical structure. Describe how hormones interact with tissues to produce a response. Describe three methods of regulating the release of hormones.
- Place the following steps (showing how a steroid hormone changes the activities of its target cells) in order of what happens first, second, third, fourth, and last. Refer to image. The hormone-receptor complex enters the nucleus of the cell and binds to the DNA. The steroid hormone passes through the cell membrane. The hormone attaches to a receptor in the cytoplasm, forming a hormone-receptor complex. A gene in the DNA is activated, and transcription and translation take place. Proteins that alter the cell′s activities, such as enzymes, are made. 2. Place the following steps (showing how a hydrophilic hormone changes the activities of its target cells) in order of what happens first, second, third, and last. Refer to image. The activity of the target cell is changed by the final enzyme in the cascade. The second messenger activates or deactivates certain enzymes in a cascade fashion. A second messenger is activated. Hormone binds to a receptor protein.Explain how mutations in the following proteins might result in either loss of responsiveness to a given hormone or production of a continuous signal even in the absence of the hormone: a mutation in a growth factor receptor with protein kinase activityExplain how aspirin can block the synthesis of prostaglandins?
- Signals carried by hormones must eventually be terminated. Describe several different mechanisms for signal termination.Which of the statements is/are incorrect for hormones? 1) Hormones are non-nutrient chemicals serving as intercellular messengers. 2) Hormones are molecules of low molecular weight and are produced in traces. 3) Hormones give energy and also effect metabolism and growth activities of target cells. 4) Many hormones are produced in inactive form.Explain what is meant by the half-life of a hormone.