The detailed mechanisms of the given reactions are to be predicted. Concept introduction: A mechanism involves the collection of all those steps that occur in a reaction. Ester formation occurs between carboxylic acid and alcohol in acidic medium. It involves protonation of the carbonyl group of carboxylic acid, and then attack of hydroxyl oxygen of alcohol on the carbonyl carbon. It involves the formation of water as another product. The amide bond contains a carbonyl group bonded to an amino group. The amide bond is a reaction product of carboxylic acid, acid chlorides or esters with primary amines . It occurs by nucleophilic attack of the carbonyl carbon by an amine group. Hydrolysis of the cyanide group in acidic medium results in the formation of the carboxylic group. The reaction occurs in presence of mineral acid and proceeds via the formation of amide as an intermediate.

Question

(a) (b) (c) Suggest a synthesis of the following alkene (A) using a Wittig reaction strategy. Draw the starting material(s), key reagent and a full reaction mechanism including an explanation of the observed geometry. Which of the following (B) and (C) will favour the enol form? Briefly explain your reasoning. Predict the product(s) and provide a mechanism for each of the following transformations: (i) (ii) OMe OMe Base OEt NaOEt

Answer 1

Question

Definition Definition Class of organic compounds that contain a carboxyl group ( - COOH ) and has a general formula R - COOH or R - CO 2 H , where R refers to the alkyl, alkenyl, aryl, or other groups. They can undergo different chemical reactions, such as acid-base reactions, esterification, and oxidation. These are essential components of living organisms, playing important roles in metabolic processes, signaling, and as pharmaceuticals.

Chapter 17, Problem 32P

Interpretation Introduction

Interpretation:

The detailed mechanisms of the given reactions are to be predicted.

Concept introduction:

A mechanism involves the collection of all those steps that occur in a reaction.

Ester formation occurs between carboxylic acid and alcohol in acidic medium. It involves protonation of the carbonyl group of carboxylic acid, and then attack of hydroxyl oxygen of alcohol on the carbonyl carbon. It involves the formation of water as another product.

The amide bond contains a carbonyl group bonded to an amino group. The amide bond is a reaction product of carboxylic acid, acid chlorides or esters with primary amines. It occurs by nucleophilic attack of the carbonyl carbon by an amine group.

Hydrolysis of the cyanide group in acidic medium results in the formation of the carboxylic group. The reaction occurs in presence of mineral acid and proceeds via the formation of amide as an intermediate.

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(a) (b) (c) Suggest a synthesis of the following alkene (A) using a Wittig reaction strategy. Draw the starting material(s), key reagent and a full reaction mechanism including an explanation of the observed geometry. Which of the following (B) and (C) will favour the enol form? Briefly explain your reasoning. Predict the product(s) and provide a mechanism for each of the following transformations: (i) (ii) OMe OMe Base OEt NaOEt

. How would you carry out each of the following syntheses: ? (a) (b)

11:43 Q1. (a) (c) (d) (b) Two stereoisomers of but-2-ene are formed when 2-bromobutane reacts with ethanolic potassium hydroxide. (i) Explain what is meant by the term stereoisomers. Library Name and outline a mechanism for the reaction of 2-bromo-2-methylpropane with ethanolic potassium hydroxide to form the alkene 2-methylpropene, (CH3)2C=CH₂ Name of mechanism Mechanism (ii) Draw the structures and give the names of the two stereoisomers of but-2-ene. Stereoisomer 1 Name (iii) Name this type of stereoisomerism. Select Name Stereoisomer 2 When 2-bromo-2-methylpropane reacts with aqueous potassium hydroxide, 2-methylpropan-2-ol is formed as shown by the following equation. CH3 H₂C-C-CH3 + KOH Br Page 2 of 14 CH3 H3C-C-CH3 + KBr ОН State the role of the hydroxide ions in this reaction. Write an equation for the reaction that occurs when CH3CH₂CH₂CH₂Br reacts with an excess of ammonia. Name the organic product of this reaction. Equation Name of product 9,284 Photos, 1,166 Videos For You…

Answer 2

Question

Definition Definition Class of organic compounds that contain a carboxyl group ( - COOH ) and has a general formula R - COOH or R - CO 2 H , where R refers to the alkyl, alkenyl, aryl, or other groups. They can undergo different chemical reactions, such as acid-base reactions, esterification, and oxidation. These are essential components of living organisms, playing important roles in metabolic processes, signaling, and as pharmaceuticals.

Chapter 17, Problem 32P

Interpretation Introduction

Interpretation:

The detailed mechanisms of the given reactions are to be predicted.

Concept introduction:

A mechanism involves the collection of all those steps that occur in a reaction.

Ester formation occurs between carboxylic acid and alcohol in acidic medium. It involves protonation of the carbonyl group of carboxylic acid, and then attack of hydroxyl oxygen of alcohol on the carbonyl carbon. It involves the formation of water as another product.

The amide bond contains a carbonyl group bonded to an amino group. The amide bond is a reaction product of carboxylic acid, acid chlorides or esters with primary amines. It occurs by nucleophilic attack of the carbonyl carbon by an amine group.

Hydrolysis of the cyanide group in acidic medium results in the formation of the carboxylic group. The reaction occurs in presence of mineral acid and proceeds via the formation of amide as an intermediate.

Expert Solution & Answer

Trending nowThis is a popular solution!

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Answer 3

Question

Definition Definition Class of organic compounds that contain a carboxyl group ( - COOH ) and has a general formula R - COOH or R - CO 2 H , where R refers to the alkyl, alkenyl, aryl, or other groups. They can undergo different chemical reactions, such as acid-base reactions, esterification, and oxidation. These are essential components of living organisms, playing important roles in metabolic processes, signaling, and as pharmaceuticals.

Chapter 17, Problem 32P

Interpretation Introduction

Interpretation:

The detailed mechanisms of the given reactions are to be predicted.

Concept introduction:

A mechanism involves the collection of all those steps that occur in a reaction.

Ester formation occurs between carboxylic acid and alcohol in acidic medium. It involves protonation of the carbonyl group of carboxylic acid, and then attack of hydroxyl oxygen of alcohol on the carbonyl carbon. It involves the formation of water as another product.

The amide bond contains a carbonyl group bonded to an amino group. The amide bond is a reaction product of carboxylic acid, acid chlorides or esters with primary amines. It occurs by nucleophilic attack of the carbonyl carbon by an amine group.

Hydrolysis of the cyanide group in acidic medium results in the formation of the carboxylic group. The reaction occurs in presence of mineral acid and proceeds via the formation of amide as an intermediate.

Expert Solution & Answer

Trending nowThis is a popular solution!

See solution

Check out sample textbook solution

Answer 4

Question

Definition Definition Class of organic compounds that contain a carboxyl group ( - COOH ) and has a general formula R - COOH or R - CO 2 H , where R refers to the alkyl, alkenyl, aryl, or other groups. They can undergo different chemical reactions, such as acid-base reactions, esterification, and oxidation. These are essential components of living organisms, playing important roles in metabolic processes, signaling, and as pharmaceuticals.

Chapter 17, Problem 32P

Interpretation Introduction