Concept explainers
To determine: The application of FISH in obtaining the telomeric chromosomes in the G2 phase of the cell cycle.
Introduction: Fluorescent in situ hybridization or FISH is the technique, which uses fluorescent probes or radioactive elements to diagnose and detect any chromosomal abnormality. For example, cancer cells are detected by this technique. Also, other abnormalities such as aneuploidy, deletions, and duplication are detected by FISH.
Explanation of Solution
Humans are the eukaryotic diploid organisms, in which 23 pairs or 46 chromosomes are present. The telomeres are the
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Chapter 17 Solutions
BIOLOGY
- Scientists often extract DNA from the nucleus of cells for analysis or use. This process breaks the cell membrane, spins the solution to remove the large particles through high g-force, adds alcohol to make the DNA less soluble aqueous solution, then spins the solution again to pull the DNA out of solution. Consider a cell in metaphase compared to a cell in rest (not in the cell cycle leading to cell division). What properties of a metaphase cell might let you extract more DNA compared to the resting cell? Are there any that might make the extraction more difficult?arrow_forwardHelping tags: Biology, development, developmental biology, plants, cell elongation How is it that there is still directional cell elongation when the cell walls are present all throughout the plant cells? * Will UPVOTE, just pls help me answer the question. Thanks.arrow_forwardJust answer, no need to explain. During prophase of mitosis Select one: A.the spindle breaks down. B.nucleoli and the nuclear envelope begin to break down. C.chromatids divide. The interval before the onset of DNA replication is Select one: A.the G1 stage. B.the S phase. C. the G2 stage.arrow_forward
- Cell Structure Reflects Function What advantages are there in having the interior of the cell divided into a number of compartments such as the nucleus, the ER, lysosomes, and so forth?arrow_forwardMatch each term with its best description. ___ cell plate a. lump of cells ___ spindle b. made of microfilaments ___ tumor c. divide plant cells ___ cleavage furrow d. spindle originates here ___ contractile ring e. dangerous metastatic cells ___ cancer f. made of microtubules ___ centrosomes g. indentation ___ telomere h. shortens with agearrow_forwardThe eukaryotic cell at left is in the process of cytoplasmic division. Is this cell from a plant or an animal? How do you know?arrow_forward
- Count 100 cells and tally them. Remember the phases you learned in Bio 31 and Anatomy? Draw a pie chart graph showing the phases of Allium root tip. Label each of the phases with the % for each phase: prophase metaphase anaphase telophase interphase provide direction of the phase progression--direction in which to read the graph so the phases of mitosis are in proper order.arrow_forwardDo you expect any color or labeling in onion cells? Why not? 2. Would you expect Lugol's Solution to stain onion cells? Why or why not? Finally, look at cheek cells. Can you find the nucleus? 3. What strikes you as different in terms of cell shape compared to onion cells or cork cells? Why do you think that is? Think about differences between animal and plant cells (Figure 4.4 and text on page 59 of your textbook).arrow_forwardHelping tags: Biology, developmental biology, development process Question: What may be concluded if a particular replacement experiment revealed no foreign growths at the site of cell mass insertion? Explain your answer. * Will UPVOTE, just please help me answer the question. Thanks.arrow_forward
- explanation of the relationship between 5 important organelles and your analogy. For Example: If my analogy is a school building, I would say that the office is the nucleus as it contains the principal and vice principals as well as all the records! - this is important because the records are like the DNA of a schoolarrow_forwardBased on your microscopic observation, how many individual cell thus the string is comprised of? What is approximate combine cell length of the cells? Remember: Always measure the cell length base on the widest/longest midsection of the cell!arrow_forwardHi, can you answer the question 1 to 5? To identify the parts of this cell structure of Tem human cells Thank youarrow_forward
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