Microbiology: A Systems Approach
5th Edition
ISBN: 9781259706615
Author: Marjorie Kelly Cowan Professor
Publisher: McGraw-Hill Education
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Chapter 16, Problem 7MCQ
Summary Introduction
Introduction:
Hypersensitivity refers to unwanted immune reactions produced by the normal immune system, such as allergies and autoimmunity. They are referred as an over-reaction of the immune system. There are four types of hyper sensitivity- Type I, also called as immediate hypersensitivity, Type II, also known as cytotoxic dependent hypersensitivity, Type III, also known as Immune Complex Reaction and Type IV, immunity also known as delayed immunity.
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A number of minor cancerous cells and infected viruses, such as Epstein Barr (EBV), are able to go undetected by cytotoxic T cell degradation by what possible mechanism?
a. the production of normal class I MHC molecule
b. helper T cell activation
c. the deactivation of the complement system
d. tumor antigen expression
e. the production of the class II major histocompatability (MHC) moledule
CHAPTER 20
The Lymphatic System and Immunity
Matching
SECTION 3 Revie w
Match each lettered term with the most closely related description.
a. opsonization
1
b. helper T cells
Two parallel pairs of polypeptide chains
Found on helper T cells
C. antibody
d. class II MHC
3
Active and passive
4 Transfer of antibodies
e. costimulation
Attacked by HIV
f. IgM
6 Enhances phagocytosis
g. class I MHC
h. IgG
7 MHC proteins present in the plasma
membranes of all nucleated cells
i. passive immunity
j. anaphylaxis
8
Differentiate into memory and plasma cells
9
MHC proteins present in the plasma
membranes of all APCS and lymphocytes
9
k. CD4 markers
10
I. acquired immunity
10 Antibodies used to determine blood type
11
m. B lymphocytes
11 Secondary binding process required for T cell activation
12
12 Accounts for 80 percent of all immunoglobulins
13
13 Circulating allergen stimulates mast cells throughout body
Match each lettered term with the
Which of the following is part of the second line of defense against pathogens?a. skin b. mucus membranesc. lysozyme in tears d. phagocytes
Which of the following does NOT have MHC class II molecules on the surface of their cell membranes? a. Macrophages.b. Dendritic cells.c. B cells.d. Helper T cells.
Chapter 16 Solutions
Microbiology: A Systems Approach
Ch. 16.1 - Define immunopathology, and describe the two major...Ch. 16.1 - Prob. 2AYPCh. 16.2 - Prob. 3AYPCh. 16.2 - Outline the steps of a type I allergic response,...Ch. 16.2 - Identify three conditions caused by IgE-mediated...Ch. 16.2 - Prob. 6AYPCh. 16.2 - Prob. 7AYPCh. 16.2 - Prob. 8AYPCh. 16.3 - List the three immune components causing cell...Ch. 16.3 - Prob. 10AYP
Ch. 16.3 - Prob. 11AYPCh. 16.4 - Prob. 12AYPCh. 16.4 - Prob. 13AYPCh. 16.5 - Prob. 14AYPCh. 16.5 - List four classes of grafts, and explain how host...Ch. 16.6 - Prob. 16AYPCh. 16.6 - Prob. 17AYPCh. 16.7 - Prob. 18AYPCh. 16.7 - Prob. 19AYPCh. 16.7 - Prob. 20AYPCh. 16 - Prob. 1MCQCh. 16 - Prob. 2MCQCh. 16 - The contact with allergen that results in symptoms...Ch. 16 - Prob. 4MCQCh. 16 - Prob. 5MCQCh. 16 - Prob. 6MCQCh. 16 - Prob. 7MCQCh. 16 - Prob. 8MCQCh. 16 - Prob. 9MCQCh. 16 - Prob. 10MCQCh. 16 - Prob. 11TFCh. 16 - Prob. 12TFCh. 16 - Prob. 13TFCh. 16 - Prob. 14TFCh. 16 - Prob. 15TFCh. 16 - Prob. 1CTQCh. 16 - Summarize the roles of the microbiome and genetics...Ch. 16 - Prob. 3CTQCh. 16 - Prob. 4CTQCh. 16 - Prob. 5CTQCh. 16 - From chapter 15. figure 15.1. How would a persons...Ch. 16 - Prob. 2VCCh. 16 - Prob. 1CM
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- Type I (immediate) hypersensitivity A. is mediated by IgE B. is mediated by T lymphocytes C. both is mediated by IgE and involves degranulation of mast cells D. involves degranulation of mast cellsarrow_forwardThe major inflammatory mediator released by degranulating mast cells in type I hypersensitivity is a. immunoglobulin b. complement c. histamine d. interleukin e. prostaglandinarrow_forwardDuring allergic sensitization, which of the following statements are FALSE? A. Allergen exposure coincides with unrelated damage B. Dendritic cells induce IL-6 production by TH2 CD4+ T cells during TH2 cell differentiation C. Damage induces the production of alarmins like IL-25 D. TFH cells bind to B cells via CD40L to CD40 and produce IL-4arrow_forward
- The detrimental effects of Lupus erythematosis are initiated by A. activated T cells attacking myelin B. immune complexes lodging in capillaries C. lack of activated CD4+ cellsarrow_forwardWhich of the following participates in an immediate rather than an induced innate immune response to infection in a human host? (Select all that apply.) a. scavenger receptors b. commensal microorganisms c. dectin-1 d. alternative pathway of complement activation e. MyD88 f. CXCL8 g. defensins h. NOD1 and NOD2 i. lectin pathway of complement activation.arrow_forwardWhich of the following statements are true for antigen presentation. a. Antigen presentation means that other cells attach the pathogen first and present it to T cells. b. Antigen-presenting cells display protein fragments, resulting from the digestion of the pathogen, in complex with MHC receptor to B cells c. Antigen presenting cells display protein fragments, resulting from the digestion of the pathogen, in complex with MHC receptor on their surface. d. Antigen-presenting cells are phagocytic cells e. Antigen presentation is required for T cell activation f. Cytokines released by macrophages are required for T cell activation g. T cell receptors recognize the MHC receptors in complex with antigen fragments displayed by antigen-presenting cells. h. Phagocytic cells are involved in innate immunity. Therefore they have no role in T-cell activationarrow_forward
- Which of the following is false about HLA class I molecules? A. They are encoded by multiple and highly polymorphic genes. B. They consist of alpha and beta chains. C. They possess beta-2 microglobulin. D. They present foreign antigens to cytotoxic T cells. E. none of the abovearrow_forwardWhich of the following explains why dendritic cells, but not macrophages or B cells, contribute to the activation of naive T cells? a. Macrophages and B cells do not express MHC class II molecules until they are activated. b. Dendritic cells upregulate B7 after engaging innate immunity receptors at sites of infection. c. Dendritic cells express higher levels of CTLA4. d. Macrophages and B cells do not process antigen. e. Dendritic cells use Toll-like receptors to hold antigen in place for extended periods of time.arrow_forwardComplement can enhance phadocytosis because of the presence on macrophages and neutrophils of receptors for: а. Factor D b. C3b c. C6 d. C9arrow_forward
- All of the following are true in reference to T- cell priming except a. it occurs in primary lymphoid organs b. it transforms naive T cells into differentiated effector T cells c. it is the first stage of a primary adaptive immune response d. it requires interaction between naive T cells and antigen-presenting cells e. it takes place in many locations including, but not limited to, lymph nodes, Peyer's patches, and the tonsils.arrow_forwardThe _____ occurs 6–8 hours after an initial type I allergic response in which mast cells produce leukotrienes, chemokines, and cytokines. a. Arthus reaction b. late-phase reaction c. delayed-type hypersensitivity reaction d. condition known as anaphylactic shock e. skin rash known as chronic urticaria.arrow_forwardThe following events occur in humoral immunity, leading to an activated B cell in a T dependent manner. Of the steps listed below, which would be step number 5 in the process. Hint: only include these steps in the numbering...order the steps and select which one is #5 A. secretion of cytokines by Th B. Receptor mediated endocytosis C. B cell receptors recognize and bind to an antigen D. Recognition by Th E. Digestion and processing of the antigen by the B cell F. Display of the antigen along with MHC proteinsarrow_forward
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