Concepts of Genetics (12th Edition)
12th Edition
ISBN: 9780134604718
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino, Darrell Killian
Publisher: PEARSON
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Chapter 16, Problem 23ESP
Summary Introduction
To propose: An experiment for differentiating two types of mutations.
Introduction: The variations caused in the genetic material of an organism from a source or randomly are called mutations. The minute changes in the DNA fragment caused the new variations among the individuals, which makes them different from each other.
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Students have asked these similar questions
The table below shows different types of mutations in different positions in four genes. Choose the letter (A to E), from the
drop-down menu, that represents the most likely type of protein that will be produced from each of these mutated genes.
A: completely normal protein
B: functional protein with ONE amino acid different from normal
C: non-functional protein with ONE amino acid different from normal
D: non-functional protein with MANY amino acids different from normal
E: no protein at all
Answer
Type of mutation
Position of mutation in gene
(A, B, C, D, or E)
before the part of the gene that specifies
the active site of the enzyme
2 base pair insertion
Inonsense
immediately before the stop codon
in the part of the gene that specifies the
active site of the enzyme
silent
1 base pair insertion
in an intron
You are working in the lab with two known carcinogens found in cigarette smoke: Benzo(a)pyren (BaP) and nitrosamine ketone (NNK). BaP is an aromatic hydrocarbon and the mechanism of carcinogenesis is through oxidation reactions with DNA. NNK is a nitrosoamine. Describe how these two kinds of carcinogens lead to mutations. (Be detailed. Remember you are graded on effort/completeness.)
A chemist synthesizes four new chemical compounds in the laboratory
and names them PFI1, PFI2, PFI3, and PFI4. He gives the PFI
compounds to a geneticist friend and asks her to determine their
mutagenic potential. The geneticist finds that all four are highly
mutagenic. She also tests the capacity of mutations produced by the PFI
compounds to be reversed by other known mutagens and obtains the
following results. What conclusions can you make about the nature of
the mutations produced by these compounds?
Reversed by
Mutations,
Nitrous,
Aminopurine acid
Acridine
orange
2-
produced
by
Hydroxylamine
PFI1
Yes
Yes
Some
No
PFI2
No
No
No
No
PFI3
Yes
Yes
No
No
PFI4
No
No
No
Yes
Chapter 16 Solutions
Concepts of Genetics (12th Edition)
Ch. 16 - Even though the lac Z, Y, and A structural genes...Ch. 16 - Predict the level of genetic activity of the lac...Ch. 16 - Prob. 1CSCh. 16 - Prob. 2CSCh. 16 - Prob. 3CSCh. 16 - HOW DO WE KNOW? In this chapter, we focused on the...Ch. 16 - Prob. 2PDQCh. 16 - Contrast positive versus negative control of gene...Ch. 16 - Contrast the role of the repressor in an inducible...Ch. 16 - For the lac genotypes shown in the following...
Ch. 16 - For the genotypes and conditions (lactose present...Ch. 16 - The locations of numerous lacI and lacIS mutations...Ch. 16 - Prob. 8PDQCh. 16 - Prob. 9PDQCh. 16 - Predict the effect on the inducibility of the lac...Ch. 16 - Erythritol, a natural sugar abundant in fruits and...Ch. 16 - Prob. 12PDQCh. 16 - Prob. 13PDQCh. 16 - Neelaredoxin is a 15-kDa protein that is a gene...Ch. 16 - The creation of milk products such as cheeses and...Ch. 16 - Both attenuation of the trp operon in E. coli and...Ch. 16 - Prob. 17PDQCh. 16 - Prob. 18ESPCh. 16 - In a theoretical operon, genes A, B, C, and D...Ch. 16 - A bacterial operon is responsible for the...Ch. 16 - A marine bacterium is isolated and shown to...Ch. 16 - Prob. 22ESPCh. 16 - Prob. 23ESP
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