Whether the brother of a newborn baby, who is affected by cystic fibrosis, is a carrier of this disease. Introduction: Cystic fibrosis is a type of autosomal recessive disease. In this disease, thick mucus is produced in lung and airway and the liver, pancreas, kidney, and intestine also get affected. The gene, which is responsible for the disease normally codes for 1,480 amino acids and the mutant gene codes for 1,479 amino acids. Only one amino acid that is phenylalanine is not produced. The baby who is suffering from cystic fibrosis has an older brother. To detect whether his brother is a carrier or not polymerase chain reaction (PCR) technique can be used.

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Chapter 15.3, Problem 1R

Summary Introduction

To determine:

Whether the brother of a newborn baby, who is affected by cystic fibrosis, is a carrier of this disease.

Introduction:

Cystic fibrosis is a type of autosomal recessive disease. In this disease, thick mucus is produced in lung and airway and the liver, pancreas, kidney, and intestine also get affected. The gene, which is responsible for the disease normally codes for 1,480 amino acids and the mutant gene codes for 1,479 amino acids. Only one amino acid that is phenylalanine is not produced. The baby who is suffering from cystic fibrosis has an older brother. To detect whether his brother is a carrier or not polymerase chain reaction (PCR) technique can be used.

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