Campbell Biology
Campbell Biology
12th Edition
ISBN: 9780135188743
Author: Urry
Publisher: PEARSON
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Chapter 15, Problem 9TYU
Summary Introduction

To know: The location of gene “a” with respect to vestigial wing locus and brown eye locus.

Introduction: A gene can be described as the unit of inheritance which is the specific segment of DNA (deoxyribonucleic acid) capable of being transcribed. These genes are present at any specific locus on DNA which is defined as the gene locus. The more specific area, or the locus, is this particular neighborhood where the gene is found.

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Assume you are mapping genes A, B, C, and D in Drosophila. You know that these genes are linked on the same chromosome, and you determine the recombination frequencies between each pair of genes to be as follows: A–B, 8%; A– C, 28%; A–D, 25%; B–C, 20%; B–D, 33%. (a) Describe how you determined the recombination frequency for each pair of genes. (b) Draw a chromosome map based on your data.
The genetic map was based on crosses in Drosophila involving the three sex-linked genes a, b and c. “a” gives red eyes, “b” gives normal wings and “c” gives black body. The recombination frequencies between these genes are as follows; a and b is 23.8, b and c is 2.6 and a and c is 28.1, respectively.  Could you draw a basic genetic map based on distance between these genes using dots to show distance(s)? Could you make one fundamental comment using these distances based on genetic linkage?
In a series of mapping experiments, the recombination frequencies for four different linked genes of the Drosophila fly were determined, as shown in the figure. Based on this information, what is the most probable order of these genes on the chromosome? b 0 cn 90 rb 3.5 6.5 0 vg 19 9.0 16 0 b cn rb vg The numbers in the boxes are the recombination frequencies in between the genes (in percent). O b-rb-cn-vg O vg-cn-b-rb Orb-cn-vg-b b = black body cn = cinnabar eyes rb = reduced bristles vg = vestigial wings O vg-b-rb-cn

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