Biology: The Unity and Diversity of Life (MindTap Course List)
15th Edition
ISBN: 9781337408332
Author: Cecie Starr, Ralph Taggart, Christine Evers, Lisa Starr
Publisher: Cengage Learning
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Chapter 14, Problem 7GP
Expression of the SRY gene on the Y chromosome gives rise to the male
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Suppose genetic analysis reveals a serious mutation in a gene in the green region of the left-hand copy of chromosome 9 in this individual. Where would you go look for another allele of this gene in this individual to see whether this individual is homozygous or heterozygous for this mutation?
Males of many diploid species (like us) have X and Y sex chromosomes. They are hemizygous for most X-
linked genes. Thus, males express most X-linked alleles, whether they are dominant or recessive in
females. In the fruit fly Drosophila, it is common to achieve the equivalent of a test cross of X-linked
genes in females by assessing the readily observed phenotypes of their male progeny. Since males do
not receive X-linked genes from their father, sires of these crosses can be normal or wild-type flies. In fly
genetics, it is conventional to name a gene after the mutant phenotype that enabled its discovery.
Your challenge is to establish gene order and map distances between three X-linked genes in Drosophila.
Each gene is represented by recessive mutant alleles that express rather distinctive phenotypes relative
to their dominant wild-type alternative alleles. Flies expressing fruitless (f) are bisexual, lush (1) have a
heightened responses to ethanol, and ken&barbie (kb) lack external…
Explain why a person with Klinefelter Syndrome (XXY) still exhibits abnormal phenotypes despite the fact that one of the extra X Chromosome is inactivated practically leaving an XY active sex chromosomes similar to a normal male?
Chapter 14 Solutions
Biology: The Unity and Diversity of Life (MindTap Course List)
Ch. 14 - Prob. 1DAACh. 14 - Prob. 2DAACh. 14 - Prob. 3DAACh. 14 - Prob. 4DAACh. 14 - Prob. 5DAACh. 14 - Prob. 1SQCh. 14 - Pedigree analysis is necessary when studying human...Ch. 14 - A recognized set of symptoms that characterize a...Ch. 14 - Prob. 4SQCh. 14 - A trait that is present in a male child but not in...
Ch. 14 - Choose the statement that is incorrect. a. A son...Ch. 14 - Prob. 7SQCh. 14 - Prob. 8SQCh. 14 - Klinefelter syndrome (XXY) can most be easily...Ch. 14 - Prob. 10SQCh. 14 - Does the phenotype indicated by the red circles...Ch. 14 - G6PD deficiency is an X-Linked recessive disorder....Ch. 14 - Marian syndrome (Section 13.5) is inherited in an...Ch. 14 - Duchenne muscular dystrophy, which is inherited in...Ch. 14 - Human females have two X chromosomes (XX); males...Ch. 14 - A mutation on an autosome causes a particular...Ch. 14 - Expression of the SRY gene on the Y chromosome...Ch. 14 - The somatic cells of most individuals with Down...Ch. 14 - Mutations in the genes for clotting factor VIII...
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- Human sex chromosomes are XX for females and XY for males. a. With respect to an X-linked gene, how many different types of gametes can a male produce? b. If a female is homozygous for an X-linked allele, how many different types of gametes can she produce with respect to this allele? c. If a female is heterozygous for an X-linked allele, how many different types of gametes can she produce with respect to this allele?arrow_forwardWhat evidence indicates that a trait is coded by a dominant allele on an autosome?arrow_forwardHuman females have two X chromosomes XX; males have one X and one Y chromosome XY. a. With respect to X-linked alleles, how many different types of gametes can a male produce? b. A female homozygous for an X-linked allele can produce how many types of gametes with respect to that allele? c. A female heterozygous for an X-linked allele can produce how many types of gametes with respect to that allele?arrow_forward
- In 1916, Dorothy Osborn suggested that pattern baldness is a sex-influenced trait that is dominant in males and recessive in females. More research suggested that pattern baldness is an X-linked recessive trait. Would you expect to see independent assortment between genetic markers on the X chromosome and pattern baldness if (a) pattern baldness is sexinfluenced and (b) if pattern baldness is X-linked recessive? Explain your answer.arrow_forward: In Drosophila, yellow body is due to an X-linked gene that is recessive to the gene forgray body.(a) A homozygous gray female is crossed with a yellow male. The F1 are intercrossed toproduce F2. Give the genotypes and phenotypes, along with the expected proportions, of theF1 and F2 progeny.(b) A yellow female is crossed with a gray male. The F1 are intercrossed to produce the F2.Give the genotypes and phenotypes, along with the expected proportions, of the F1 and F2progeny.(c) A yellow female is crossed with a gray male. The F1 females are backcrossed with graymales. Give the genotypes and phenotypes, along with the expected proportions, of the F2progeny.(d) If the F2 flies in part b mate randomly, what are the expected phenotypic proportions offlies in the F3??arrow_forwardLet’s suppose that a gene affecting pigmentation is found on the Xchromosome (in mammals or insects) or the Z chromosome (in birds)but not on the Y or W chromosome. It is found on an autosome inbees. This gene exists in two alleles: D (dark) is dominant to d (light).What would be the phenotypic results of crosses between true-breedingdark females and true-breeding light males, and the reciprocal crossesinvolving true-breeding light females and true-breeding dark males,in the following species? Refer back to Figures 4.1 and 4.2 for themechanism of sex determination in these species.A. BirdsB. Fruit fliesC. BeesD. Humansarrow_forward
- What is a Barr body? How many Barr bodies in a person with genotype XXXXX? How is the structure of a Barr body different from that of other chromosomes in the cell? How does the structure of a Barr body affect gene expression? Color-blindness is an X-linked recessive trait. Heterozygous females are not color blind but they can sometimes have partial color blindness. Explain how this can occur.arrow_forwardLet’s suppose that a gene affecting pigmentation is found on the Xchromosome (in mammals or insects) or the Z chromosome (inbirds) but not on the Y or W chromosome. It is found on an autosome in bees. This gene exists in two alleles: D (dark) is dominant tod (light). What would be the phenotypic results of crosses betweentrue-breeding dark females and true-breeding light males and of thereciprocal crosses involving true-breeding light females and truebreeding dark males for each of the following species?A. Birds C. BeesB. Fruit flies D. Humansarrow_forwardIn humans, one of the genes determining color vision islocated on the X chromosome. The dominant form (C )produces normal color vision; red-green color deficiency(c) is recessive. If a man with normal color visionmarries a color-deficient woman, what is the probabilityof them having a color-deficient son? A color-deficientdaughter?arrow_forward
- Let’s say there is an organism with two pairs of alleles, W/w and Z/z, each pair is located on a different pair of chromosomes in the organism’s somatic cells. During Metaphase, what will you observe in the somatic cells?arrow_forwardBow-legs is hypothesized to be X-linked recessive trait in Drosophila melanogaster. The P1 virgin females were, once again, homozygous wild type but the males were bow-legged. There were 52 wild type males and 67 wild type females in the F1 generation. The F2 generation contained 30 wild type males, 75 wild type females, 40 bow-legged males and no bow-legged females. Is this what is to be expected? Use chi-square to prove your position.arrow_forwardDefine the Random Monoallelic Expression: Inactivation of the X Chromosome ?arrow_forward
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