Biology: The Unity and Diversity of Life (MindTap Course List)
15th Edition
ISBN: 9781337408332
Author: Cecie Starr, Ralph Taggart, Christine Evers, Lisa Starr
Publisher: Cengage Learning
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Chapter 14, Problem 4SQ
Summary Introduction
Introduction: Tay–Sachs disease is caused due to mutations in the HEXA gene that encodes lysosomal enzyme. It follows autosomal recessive inheritance, that is, two copies of mutated gene are required for the occurrence of the disease.
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Duchenne muscular dystrophy is sex linked and usually affects only males. Victims of the disease become progressively weaker, starting early in life.a. What is the probability that a woman whose brother has Duchenne’s disease will have an affected child?b. If your mother’s brother (your uncle) had Duchenne’s disease, what is the probability that you have received the allele?c. If your father’s brother had the disease, what is the probability that you have received the allele?
15. The following pedigree shows inheritance of Huntington's disease, a fatal genetic
disorder that causes neurodegeneration. Since signs and symptoms usually do not
appear until adulthood, many who are carriers may not realize their risk of passing on
the disease-causing allele. The following pedigree represents a family in which some
people are affected by Huntington's disease.
Reeessive Trit
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Fragile X syndrome is an X-linked recessive Achondroplasia is an autosomal dominant trait characterized by a shortened stature. An XX individual is a carrier for Fragile X disorder and is unaffected by achondroplasia. An XY individual is not affected by Fragile X disorder and has achondroplasia.
a. What is the XX individual’s genotype
b. What is the XY individual’s genotype?
c. If the two individuals where to have children, what are the possible genotypes and phenotypes of their children? Use a Punnett square.
d. What is the probability of them having a child with Fragile X and achondroplasia?
Chapter 14 Solutions
Biology: The Unity and Diversity of Life (MindTap Course List)
Ch. 14 - Prob. 1DAACh. 14 - Prob. 2DAACh. 14 - Prob. 3DAACh. 14 - Prob. 4DAACh. 14 - Prob. 5DAACh. 14 - Prob. 1SQCh. 14 - Pedigree analysis is necessary when studying human...Ch. 14 - A recognized set of symptoms that characterize a...Ch. 14 - Prob. 4SQCh. 14 - A trait that is present in a male child but not in...
Ch. 14 - Choose the statement that is incorrect. a. A son...Ch. 14 - Prob. 7SQCh. 14 - Prob. 8SQCh. 14 - Klinefelter syndrome (XXY) can most be easily...Ch. 14 - Prob. 10SQCh. 14 - Does the phenotype indicated by the red circles...Ch. 14 - G6PD deficiency is an X-Linked recessive disorder....Ch. 14 - Marian syndrome (Section 13.5) is inherited in an...Ch. 14 - Duchenne muscular dystrophy, which is inherited in...Ch. 14 - Human females have two X chromosomes (XX); males...Ch. 14 - A mutation on an autosome causes a particular...Ch. 14 - Expression of the SRY gene on the Y chromosome...Ch. 14 - The somatic cells of most individuals with Down...Ch. 14 - Mutations in the genes for clotting factor VIII...
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
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- Duchenne muscular dystrophy is sex linked and usuallyaffects only males. Victims of the disease become progressively weaker, starting early in life.a. What is the probability that a woman whose brotherhas Duchenne’s disease will have an affected child?b. If your mother’s brother (your uncle) had Duchenne’sdisease, what is the probability that you have receivedthe allele?c. If your father’s brother had the disease, what is theprobability that you have received the allele?arrow_forwardA woman with a rare autosomal recessive disorder was told that it was unlikely that her children would have the disorderas her husband did not have it. However, her first child has the disorder. a. What is the most likely explanation? b. Diagram the cross between the woman and her husband using a Punnett square, give the genotypic ratio (GR) and phenotypic ratio (PR) from the Punnett square. c. Based on the Punnett square results, what is the chance that her next child will have the disorder?arrow_forwardIf a genetic disease is inherited as an autosomal recessive, one would expect to find which of the following? A. Two affected individuals never have an unaffected child. B. Two affected individuals have affected male offspring but no affected female children. C. If a child has the disease, one of his or her grandparents will have had it. D. In a marriage between an affected individual and an unaffected one, all the children are unaffected.arrow_forward
- Fruit flies are very useful model organisms that have been used to study genetics. One mutant recessive trait in fruit flies is called "eyeless" because it causes flies to have no eyes. Cross an eyeless fly with a homozygous normal fly. a. Draw the Punnett square. b. What is the genotyoe ratio of the offspring? c. What is the phenotype ratio of the offspring? d. What genetic problem is this? (monohybrid, dihybrid or multiple allele)arrow_forwardWebbed fingers is inherited as an X-linked disease An unaffected male marries an affected female. a. Draw a Punnett square of the possible offspring. b. List the phenotypes of the possible children c. Draw a pedigree that displays the inheritance in you Punnett squarearrow_forwarda. What is the type of inheritance? b. What is known of the genotype of the male in the above cross? c. What is known of the genotype of the female in the above cross? d. Provide map distances if possible.arrow_forward
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