Concept explainers
Both members of a couple know that they are carriers of the cystic fibrosis allele. None of their three children has cystic fibrosis, but any one of them might be a carrier The couple would like to have a fourth child but are worried that he or she would very likety have the disease, since the first three do not. What would you tell the couple? Would it remove some uncertainty from their prediction if they could find out whether the three children are carriers?
Want to see the full answer?
Check out a sample textbook solutionChapter 14 Solutions
Campbell Biology
Additional Science Textbook Solutions
Genetics: Analysis and Principles
Becker's World of the Cell (9th Edition)
Microbiology with Diseases by Body System (4th Edition)
Human Anatomy & Physiology (2nd Edition)
Fundamentals of Anatomy & Physiology (11th Edition)
Genetic Analysis: An Integrated Approach (2nd Edition)
- A young couple went to see a genetic counselor because each had a sibling affected with cystic fibrosis. (Cystic fibrosis is a recessive disease and neither member of the couple nor any of their four parents is affected). What is the probability that the female of this couple is a carrier and what are the chances that their child will be affected with cystic fibrosis?arrow_forwardSickle cell anemia is a human genetic disorder caused by an autosomal recessive allele. A couple plan to marry and want to know the probability that they will have an affected child. With your knowledge of Mendelian inheritance, what can you tell them if (1) each has one affected parent and a parent with no family history of SCA or (2) the man is affected by the disorder but the woman has no family history of SCA?arrow_forwardCystic Fibrosis (CF) is an autosomal recessive condition. Therefore, heterozygous (Cc) carriers do not display symptoms. Two parents who are carriers plan to start a family and you are a genetic counselor helping to advise them about their chances of having children affected by CF. a) Suppose the couple has 4 children, each one year apart. What is the probability that all 4 children will inherit CF? b) What is the probability that any 3 of their 4 children will not inherit CF, but 1 will be affected? c) What is the probability that their first child will not inherit CF, but the younger 3 children will inherit CF?arrow_forward
- Jan and Michael are both carriers for the cystic fibrosis allele. If Jan and Michael have five children, what the probability that three or more of the children will have the disease?arrow_forwardThe e-gram (graph to the right of allelic ladder image) and above is from a woman. She has variations 14 and 15 at STR D3S1358. If she has children with a man who has variations 12 and 19 at the same STR, what are the possible combinations of variations that their children would have?arrow_forwardKaren and Steve each have a sibling with sickle-cell disease.Neither Karen nor Steve nor any of their parents have thedisease, and none of them have been tested to see if they carrythe sickle-cell allele. Based on this incomplete information,calculate the probability that if this couple has a child, thechild will have sickle-cell disease.arrow_forward
- A young couple went to see a genetic counselor because each had a sibling affected with cystic fibrosis. (Cystic fibrosis is a recessive disease, and neither member of the couple nor any of their four parents is affected.) a. What is the probability that the female of this couple is a carrier? b. What are the chances that their child will be affected with cystic fibrosis? c. What is the probability that their child will be a carrier of the cystic fibrosis mutation?arrow_forwardA couple, who are both normal, have a daughter who is albino and a son who is normal. a) what is the probability that their normal son is a carrier of the albinism gene? Show your work. b) the couple wants to have 3 more children; what is the probability that they will have 3 normal girls? Show your work.arrow_forwardA young couple went to see a genetic counselor because each had a sibling with cystic fibrosis. (Cystic fibrosis is a recessive disease, and neither member of the couple nor any of their four parents is affected.) What is the probability that the female of this couple is a carrier? What are the chances that their child will have cystic fibrosis? 3. What is the probability that their child will be a carrier of the cystic fibrosis disease allele?arrow_forward
- Both members of a couple know that they are carriers of the cysticfibrosis allele. None of their three children has cystic fibrosis, but anyone of them might be a carrier. The couple would like to have a fourthchild but are worried that he or she would very likely have the disease,since the first three do not. What would you tell the couple? Would itremove some uncertainty from their prediction if they could find outwhether the three children are carriers?arrow_forwardMary and Ron don't have albinism. However, is it possible for them to have a child with albinism? Explain. Stephanie has normal color vision. Her husband Chris also has normal color vision. They have a son that is color blind and a daughter that has normal color vision. What is the genotype of the mother, father, son and the daughter? Andy and Anne do not have polydactyl. Is it possible for them to have a child with polydactyl? Explain. When examining a pedigree chart, I notice that only males are affected. What does this tell me about the inheritance pattern? A man with blood type A marries a woman with blood type B. Their child has blood type O. What are the genotypes of the parents?arrow_forwardI will be adding two questions here because I asked two of the same questions twice by accident earlier. A man and a woman do not have hemophilioa, but the womans father did. (Hemophilia is X-linked recessive). a) What is the probability that they will have a child with hemophilia? b) Is it possible for any of their daughters to be affected? Explain. A cross between a horse homozygous for red hair and a horse homozygous for white hair results in offspring with the coat colour called roan. When you look at the fur of the roan offspring you see both red and white hairs. What type of inheritance best explains this? a) blending inheritance b)codominance c)incomplete codominance d)multiple allelesarrow_forward