Both members of a couple know that they are carriers of the cysticfibrosis allele. None of their three children has cystic fibrosis, but anyone of them might be a carrier. The couple would like to have a fourthchild but are worried that he or she would very likely have the disease,since the first three do not. What would you tell the couple? Would itremove some uncertainty from their prediction if they could find outwhether the three children are carriers?

Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN:9781305251052
Author:Michael Cummings
Publisher:Michael Cummings
Chapter10: From Proteins To Phenotypes
Section10.7: Defects In Transport Proteins: Hemoglobin
Problem 2EG
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Both members of a couple know that they are carriers of the cystic
fibrosis allele. None of their three children has cystic fibrosis, but any
one of them might be a carrier. The couple would like to have a fourth
child but are worried that he or she would very likely have the disease,
since the first three do not. What would you tell the couple? Would it
remove some uncertainty from their prediction if they could find out
whether the three children are carriers?

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