Biology
5th Edition
ISBN: 9781260487947
Author: BROOKER
Publisher: MCG
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Textbook Question
Chapter 13, Problem 10TY
Abnormalities in the expression of ncRNAs are associated with
- a. many forms of cancer.
- b. neurological disorders.
- c. cardiovascular diseases.
- d. all of the above.
- e. only a and b.
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When an ncRNA functions as a decoy, ita. contains binding sites for many different proteins, therebypromoting the formation of a large complex.b. recognizes other ncRNAs and sequesters them, therebypreventing them from working.c. can alter its conformation, allowing it to switch betweenactive and inactivate conformations.d. may physically prevent or block a cellular process fromhappening.
Alternative RNA splicing
a. is a mechanism for increasing the rate of transcription.
b. can allow the production of proteins of different sizes from a gene.
C. can allow the production of similar proteins from different RNAS.
d. increases the rate of transcription.
e. is due to the presence or absence of particular snRNAs.
Unusually high levels of Mdr1 provide stem cells with
a. Nutrients needed
b. Protection of their genomes from mutagenic agents
c. Apoptotic factors
d. Ability to differentiate
Chapter 13 Solutions
Biology
Ch. 13.1 - Prob. 1CCCh. 13.2 - Prob. 1CCCh. 13.3 - Prob. 1EQCh. 13.3 - Prob. 2EQCh. 13.3 - Prob. 3EQCh. 13.3 - Effects of Non-coding RNAs on Translation and mRNA...Ch. 13.4 - Non-coding RNAs and Protein Sorting Core Skill:...Ch. 13.5 - Core Skill: Modeling The goal of this modeling...Ch. 13 - Prob. 1TYCh. 13 - Prob. 2TY
Ch. 13 - Prob. 3TYCh. 13 - Prob. 4TYCh. 13 - Prob. 5TYCh. 13 - Prob. 6TYCh. 13 - With regard to miRNAs and siRNAs, which of the...Ch. 13 - Cas1 and Cas2 proteins play a role during which of...Ch. 13 - Which of the following components bind to...Ch. 13 - Abnormalities in the expression of ncRNAs are...Ch. 13 - An ncRNA may have one or more of the following...Ch. 13 - What is RNA interference (RNAi)? Explain how the...Ch. 13 - Prob. 3CQCh. 13 - Prob. 1COQCh. 13 - Go to the PubMed website and search for non-coding...
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- Consider the genes that specify the structure of hemoglobin. Arrange the following events in the most likely sequence in which they would take place.a. Anemia is observed.b. The shape of the oxygen-binding site is altered.c. An incorrect codon is transcribed into hemoglobinmRNA.d. The ovum (female gamete) receives a high radiationdose.e. An incorrect codon is generated in the DNA of ahemoglobin gene.f. A mother (an X-ray technician) accidentally stepsin front of an operating X-ray generator.g. A child dies.h. The oxygen-transport capacity of the body is severelyimpaired.i. The tRNA anticodon that lines up is one of a typethat brings an unsuitable amino acid.j. Nucleotide-pair substitution occurs in the DNA of agene for hemoglobinarrow_forwardAnswers the following questions below: enhancers are: A.Proteins B.DNA regions C. Neither D. Both 2. mediators are: A. proteins B. DNA regions C. Neither D. Botharrow_forwardThe effects of transposons can includeA. disruption of gene expression.B. prevention of gene expression.C. occurrence of inversions.D. occurrence of deletions.E. all of the abovearrow_forward
- Distant regulatory sites are called: a. Enhancers b. Operators c. Both a and b d. None of the abovearrow_forwardDifferential RNA splicing may result in: a. A shift in the ratio of mRNA produced from two neighboring genes b. Inversion of exons in the mature mRNA c. Production of the same protein from two different genes d. Production of two different proteins with different properties from a single genearrow_forwardList five types of cancer in which ncRNAs can be involved.arrow_forward
- How does reverse methylation affect gene expression? Select one: o a. The gene is turned off, but still expresses a protein product. b. The gene becomes transcriptionally silent. c. There is no effect on the gene. d. The gene is hyperactive resulting in a gain of function. e. The gene expresses the wrong protein. Clear my choice How do microRNAs regulate epigenetic mechanisms during development? Select one: o a. MicroRNAs function as gene repressors b. You only find microRNAS in epigenetic and cancer cells c. MicroRNAs function as gene activators d. MicroRNAS regulate methylation on the DNA sequences of embryos e. Researchers find that when microRNAs are present the effects of epigenetic modifications are 50% greater Clear my choicearrow_forwardChanges in a cell that affect micro RNAs lead to cancer because miRNAs... a. help a cell to maintain a tight control on protein levels in a cell. b. decrease the level of a specific protein. c. increase the level of a specific protein. d. prevent the Warburg effect.arrow_forwardProvide the SIGNIFICANT differences between the following: 1. Regulation AFTER transcription mRNA processing miRNAs a. b. 2. Types of Genes Facultative Constitutive a. b.arrow_forward
- After treating cells in tissue culture with an HDAC inhibitor, which of the following is the most likely outcome? A. Repression of transcription B. Promoter methylation C. Enhanced splicing D. Activation of transcription E. Depends on the cell typearrow_forwardThe main target for Cas9 to cleave is: O a. Spacer DNA sequence O b. TracrRNA sequence C. CRRNA loop d. CRRNA sequence PAM sequence e. CLEAR MY CHOICE Which one of the following applies to the DutUng E. Coli cells a. N-glycosylase is intact. b. dATPase is not produced. С. The dUTPase is disrupted. O d. They express both dUTPase and N-glycosylase. О е. dTTPase is inactive. CLEAR MY CHOICEarrow_forward1. Transcription: a)State the role of RNA polymerase in gene transcription.b. Explain why the DNA is not used directly for protein translation (i.e., why is mRNA used instead?).c. Explain what occurs when a gene’s promoter region is open for RNA polymerase binding.d. Explain what occurs when a gene’s promoter regions is blocked from binding RNA polymerase.e. Explain how two cells, such as liver cells and skin cells, can become specialized in structure and function despite containing the same genome.arrow_forward
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