Anatomy & Physiology
1st Edition
ISBN: 9781938168130
Author: Kelly A. Young, James A. Wise, Peter DeSaix, Dean H. Kruse, Brandon Poe, Eddie Johnson, Jody E. Johnson, Oksana Korol, J. Gordon Betts, Mark Womble
Publisher: OpenStax College
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Chapter 12, Problem 8ILQ
Watch this video (http://openstaxcollege.org/l/neurotrans) to learn about the release of a neurotransmitter. The action potential reaches the end of the axon, called the axon terminal, and a chemical signal is released to tell the target cell to do something, either initiate a new action potential, or to suppress that activity. In a very short space, the electrical signal of the action potential is changed into the chemical signal of a neurotransmitter, and then back to electrical changes in the target cell membrane. What is the importance of voltage-gated calcium channels in the release of neurotransmitters?
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Watch this video (http://openstaxcollege.org/l/neurotrans) to learn about the release of a neurotransmitter. The action potential reaches the end of the axon, called the axon terminal, and a chemical signal is released to tell the target cell to do something—either to initiate a new action potential, or to suppress that activity. In a very short space, the electrical signal of the action potential is changed into the chemical signal of a neurotransmitter and then back to electrical changes in the target cell membrane. What is the importance of voltage-gated calcium channels in the release of neurotransmitters?
Explain what happens when an action potential reaches the axon terminus (terminal) by activating the receptors on the postsynaptic membrane.
Explanation addressing the question above
When an action potential, or nerve impulse, arrives at the axon terminal, it activates voltage-gated calcium channels in the cell membrane. Which is present at a much higher concentration outside the neuron than inside, rushes into the cell. The Ca2+ allows synaptic vesicles to fuse with the axon terminal membrane, releasing neurotransmitters into the synaptic cleft. The molecules of neurotransmitters diffuse across the synaptic cleft and bind to receptor proteins on the postsynaptic cell. Activation of postsynaptic receptors leads to the opening or closing of ion channels in the cell membrane. This may be depolarizing, making the inside of the cell more positive, or hyperpolarizing making the inside more negative depending on the ions involved. The excitatory and inhibitory postsynaptic potentials…
View the University of Michigan WebScope (http://openstaxcollege.org/l/nervefiber) to see an electron micrograph of a cross-section of a myelinated nerve fiber. The axon contains microtubules and neurofilaments that are bounded by a plasma membrane known as the axolemma. Outside the plasma membrane of the axon is the myelin sheath, which is composed of the tightly wrapped plasma membrane of a Schwann cell. What aspects of the cells in this image react with the stain to make them a deep, dark, black color, such as the multiple layers that are the myelin sheath?
Chapter 12 Solutions
Anatomy & Physiology
Ch. 12 - In 2003, the Nobel Prize in Physiology or Medicine...Ch. 12 - Visit this site...Ch. 12 - Visit this site...Ch. 12 - View the University of Michigan Webscope...Ch. 12 - What happens across the membrane of an...Ch. 12 - Visit this site...Ch. 12 - Watch this video...Ch. 12 - Watch this video...Ch. 12 - Which of the following cavities contains a...Ch. 12 - Which structure predominates in the white matter...
Ch. 12 - Which part of a neuron transmits an electrical...Ch. 12 - Which term describes a bundle of axons in the...Ch. 12 - Which functional division of the nervous system...Ch. 12 - What type of glial cell provides myelin for the...Ch. 12 - Which part of a neuron contains the nucleus?...Ch. 12 - Which of the following substances is least able to...Ch. 12 - What type of glial cell is the resident macrophage...Ch. 12 - What two types of macromolecules are the main...Ch. 12 - If a thermoreceptor is sensitive to temperature...Ch. 12 - Which of these locations is where the greatest...Ch. 12 - How long does all the signaling through the...Ch. 12 - What is the target of an upper motor neuron?...Ch. 12 - What ion enters a neuron causing depolarization of...Ch. 12 - Voltage-gated Na+ channels open upon leaching what...Ch. 12 - What does a ligand-gated channel require in order...Ch. 12 - What does a mechanically gated channel respond to?...Ch. 12 - Which of the following voltages would most likely...Ch. 12 - Which of the following is probably going to...Ch. 12 - How much of a change in the membrane potential is...Ch. 12 - A channel opens on a postsynaptic membrane that...Ch. 12 - What neurotransmitter is released at the...Ch. 12 - What type of receptor requires an effector protein...Ch. 12 - Which of the following neurotransmitters is...Ch. 12 - What responses are generated by the nervous system...Ch. 12 - When eating food, what anatomical and functional...Ch. 12 - Multiple sclerosis is a demyelinating disease...Ch. 12 - Which type of neuron, based on its shape, is best...Ch. 12 - Sensory fibers, or pathways, are referred to as...Ch. 12 - If a person has a motor disorder and cannot move...Ch. 12 - What does it mean for an action potential to be an...Ch. 12 - The conscious perception of pain is often delayed...Ch. 12 - If a postsynaptic cell has synapses from five...Ch. 12 - Why is the receptor the important element...
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- Neurons contain ________, which can receive signals from other neurons. a. axons b. mitochondria c. dendrites d. Golgibodiesarrow_forwardWhen action potentials arrive at a synapse between a neuron and another cell, they stimulate the release of molecules of a ________ that diffuse over to that cell.arrow_forwardA neuron responds to adequate stimulation with _______, a type of self-propagating signal.arrow_forward
- A _______________ is a drug that causes temporary paralysis by blocking the transmis- sion of nerve stimuli to the muscles. neuromuscular blocker skeletal muscle relaxantarrow_forwardVisit this site (http://openstaxcollege.org/l/nervetissue3) to learn about how nervous tissue is composed of neurons and glial cells. Neurons are dynamic cells with the ability to make a vast number of connections, to respond incredibly quickly to stimuli, and to initiate movements on the basis of those stimuli. They are the focus of intense research because failures in physiology can lead to devastating illnesses. Why are neurons only found in animals? Based on what this article says about neuron function, why wouldn't they be helpful for plants or microorganisms?arrow_forwardWhen they are not being stimulated, neurons have an electrical charge across their membranes called the resting potential. This potential is______ charged inside. When a neuron receives a sufficiently large stimulus, and reaches a potential called the_______ , it produces an action potential. This causes the neuron to become_____ charged inside.arrow_forward
- This is a biology question regarding nerve impulses. Neurofibromatosis type 1 is a condition where tumours can grow in the nerves near the skin. The growth of tumours prevents the action potentials from quickly travelling through the neurons. Identify the nerve structure from the image below and the division of the nervous system affected by neurofibromatosis type 1. CNS = Central Nervous System PNS = Peripheral Nervous System Select one: a. Nerve Structure Division of Nervous System 3 PNS b. Nerve Structure Division of Nervous System 4 CNS c. Nerve Structure Division of Nervous System 5 PNS d. Nerve Structure Division of Nervous System 1 CNSarrow_forwardImagine an experiment in which the neurons pictured here are bathed in a solution containing a nerve poison. The presynaptic neuron is stimulated and produces an action potential, but this does not result in a PSP in the postsynaptic neuron. When the experimenter adds some neurotransmitter to the synapse, the postsynaptic neuron still produces no PSP. How does the poison act to disrupt nerve function?arrow_forwardAn action potential has reached the axon terminal of a presynaptic cell. As a result of the action potential you would expect the movement of __________ into the presynaptic cell and the movement of __________ out of the presynaptic cell. Calcium : neurotransmitter Sodium : calcium Neurotransmitter : calcium Sodium : neurotransmitterarrow_forward
- Neuron A is an inhibitory neuron that is activated when the person feels heat in the tip of their index finger. Neuron A sends signals to neuron B (the postsynaptic neuron). First consider how a stimulus impacts the firing rate of neuron A. For example, when the person touches ice with their index finger vs. when the person touches a hot cup of coffee with their index finger? How would each of these impact the frequency of action potentials, the size of action potentials and the amount of neurotransmitter released. Second, consider Drug-D that causes all sodium channels in neurons to close immediately. How would taking Drug-D affect the firing rate of neuron A when the person touches a hot pan? In turn, how would this affect the firing rate of post-synaptic neuron B? Rubric: Impact of heat on A Impact of ice on A ( Impact of drug X on A Impact of drug X on B 1arrow_forwardYou are investigating the effects of a newly discovered cell type. You have an intact synapse (including pre- and post-synaptic neurons) in a dish and observe what happens upon electrical stimulation. Following electrical stimulation of the pre-synaptic neuron, you record an action potential in the pre-synaptic neuron and an EPSP in the post-synaptic neuron. The synapse most likely utilizes which of the following neurotransmitters? Sodium (Na++) GABA Calcium (Ca++) Glutamatearrow_forwarda channel can be gated mechanically, voltage or by a ligand. When you hear a sound all three of these type channels are being utilized. Explain generally where/how each of these channels are being utilized starting from hearing the sound, through travelling down a nerve to transmission to another nerve.arrow_forward
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