Becker's World of the Cell (9th Edition)
9th Edition
ISBN: 9780321934925
Author: Jeff Hardin, Gregory Paul Bertoni
Publisher: PEARSON
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Chapter 12, Problem 12.7PS
QUANTITATIVE Virus Entry by Endocytosis. Australian bat lyssavirus (ABLV), a virus closely related to rabies virus, causes neurodegeneration in humans. It has a surface glycoprotein that mediates attachment to and internalization into host cells via receptor-mediated endocytosis.
(a) Investigators have tested whether dynamin is required for ABLV infection of cells. Cultured human embryonic kidney cells were treated with dynasore, a specific inhibitor of dynamin, before being infected with a virus expressing the ABLV glycoprotein. Do the resulting data (Figure 12-25a, left) indicate dynamin involvement? Explain your answer.
(b) As a control, the researchers monitored cell viability at varying dynasore concentrations (Figure 12-25a, right). Why was this control necessary?
(c) They then used chlorpromazine, a chemical that blocks the assembly of clathrin-coated pits, in similar tests. Are the results (Figure 12-25b) consistent with those results in part a? Why or why not?
Figure 12-25 Effect of Inhibitors on Viral Entry into Cells.
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Please help me with this question. More than one answer may be correct.
The cis golgi compartment ______.
Options:
A)
is a convenient place to store tools in small cars.
B)
uses clathrin as a coating protein to send vesicles to the medial compartments.
C)
sends proteins to their proper destination.
D)
is continuous with the trans compartment.
E)
adds specific signal to proteins destine for the lysosomes.
Remember for T/F questions, either answer TRUE or FALSE, but if the answer is FALSE make sure to explain WHY the answer is false.
Proteins that were made to be sorted OUT of the endoplasmid reticulum (ER) do NOT have a retention signal so that the protein
can leave the ER.
comprehension) A scientist hypothesized that her vaccine would stimulate the immune system to attack melanoma (skin cancer) tumors and reduce their growth. To test the hypothesis, 100 melanoma patients were injected with the vaccine in a saline solution (Group A) and 100 melanoma patients were injected with only the saline solution
Chapter 12 Solutions
Becker's World of the Cell (9th Edition)
Ch. 12 - How do differences in the structure and...Ch. 12 - Why is it necessary for material flowing through...Ch. 12 - What problems would you likely see in cells...Ch. 12 - What features of membrane lipids and proteins...Ch. 12 - Based on what you learned in this chapter about...Ch. 12 - How would an inhibitor of membrane fusion...Ch. 12 - What intracellular transport processes would you...Ch. 12 - What problems would a cell have if it could not...Ch. 12 - Although the plant vacuole resembles the lysosome...Ch. 12 - Why is it important for the biochemical reactions...
Ch. 12 - Compartmentalization of Function. Each of the...Ch. 12 - Endoplasmic Reticulum. For each of the following...Ch. 12 - Biosynthesis of Integral Membrane Proteins. In...Ch. 12 - Coated Vesicles in Intracellular Transport. For...Ch. 12 - QUANTITATIVE Interpreting Data. Each of the...Ch. 12 - Cellular Digestion. For each of the following...Ch. 12 - QUANTITATIVE Virus Entry by Endocytosis....Ch. 12 - Prob. 12.8PSCh. 12 - Sorting Proteins. Specific structural features tag...Ch. 12 - Prob. 12.10PSCh. 12 - Whats Happening? Researchers have discovered a...
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