Concept explainers
(a)
To determine: The way by which fibers get into the lysosome.
Introduction: Silicosis is a type of disease which occurs due to the ingestion of silica particles like glass or sand by macrophages cells present in the lungs. Asbestos is a disease which is caused due to the inhalation of asbestos fibers. Both types of particles are found in the lysosome.
(b)
To determine: The effect of particle or fiber accumulation on the lysosome.
Introduction: Silicosis is a type of disease which occurs due to the ingestion of silica particles like glass or sand by macrophages cells present in the lungs. Asbestos is a disease which is caused due to the inhalation of asbestos fibers. Both types of particles are found in the lysosome.
(c)
To determine: The reason for the death of silica-containing or asbestos-containing cells.
Introduction: Silicosis is a type of disease which occurs due to the ingestion of silica particles like glass or sand by macrophages cells present in the lungs. Asbestos is a disease which is caused due to the inhalation of asbestos fibers. Both types of particles are found in the lysosome.
(d)
To determine: The fate of silica or asbestos fibers when silica-containing and asbestos-containing cells die. Also, determine that how the process of cell death remains continue even after the prevention of further exposure to silica dust or asbestos fibers.
Introduction: Silicosis is a type of disease which occurs due to the ingestion of silica particles like glass or sand by macrophages cells present in the lungs. Asbestos is a disease which is caused due to the inhalation of asbestos fibers. Both types of particles are found in the lysosome.
(e)
To determine: The deposition of collagen nodules in the lungs of silicosis patients.
Introduction: Silicosis is a type of disease which occurs due to the ingestion of silica particles like glass or sand by macrophages cells present in the lungs. Asbestos is a disease which is caused due to the inhalation of asbestos fibers. Both types of particles are found in the lysosome.
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Becker's World of the Cell (9th Edition)
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