SEELEY'S ANATOMY+PHYSIOLOGY
12th Edition
ISBN: 9781260172195
Author: VanPutte
Publisher: RENT MCG
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Question
Chapter 11.6, Problem 51AYP
Summary Introduction
To determine:
The meaning of the term “neuromodulator” and the way by which drugs help in regulating the action of neurotransmitters with related examples.
Introduction:
Many substances have been identified as neurotransmitters whereas others are considered as suspected neurotransmitters. The neurotransmitters are released from the presynaptic terminals whereas neuromodulators have a different pathway of release.
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Give some examples of howdrugs can modulate the action of neurotransmitters.
Why neurotransmitters are important? Cite at least 3 examples.
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Chapter 11 Solutions
SEELEY'S ANATOMY+PHYSIOLOGY
Ch. 11.1 - List and give examples of the general functions of...Ch. 11.2 - Name the components of the CNS and the PNS.Ch. 11.2 - What are the following: sensory receptor, nerve,...Ch. 11.2 - Based on the direction they transmit action...Ch. 11.2 - Based on the structures they supply, what are the...Ch. 11.2 - Where are the cell bodies of sensory, somatic...Ch. 11.2 - What are the subcategories of the ANS?Ch. 11.2 - Compare the general functions of the CNS and the...Ch. 11.3 - Describe and give the function of a neuron cell...Ch. 11.3 - What is the function of the trigger zone?
Ch. 11.3 - Prob. 11AYPCh. 11.3 - Describe the three types of neurons based on...Ch. 11.3 - Prob. 13AYPCh. 11.3 - What characteristic makes glial cells different...Ch. 11.3 - Which glial cells are found in the CNS? In the...Ch. 11.3 - Which type of glial cell Supports neurons and...Ch. 11.3 - Name the different kinds of glial cells that ore...Ch. 11.3 - Prob. 18AYPCh. 11.3 - How do myelinated axons differ from unmyelinated...Ch. 11.4 - What makes up gray matter and white matter?Ch. 11.4 - Prob. 21AYPCh. 11.5 - Describe the concentration differences for Na+ and...Ch. 11.5 - Prob. 23AYPCh. 11.5 - Describe leak ion channels and go ted ion...Ch. 11.5 - Define ligand, receptor, and receptor site.Ch. 11.5 - What kinds of stimuli cause gated ion channels to...Ch. 11.5 - Prob. 27AYPCh. 11.5 - Prob. 28AYPCh. 11.5 - Prob. 29AYPCh. 11.5 - What happens to cause depolarization and...Ch. 11.5 - Prob. 31AYPCh. 11.5 - Prob. 32AYPCh. 11.5 - How does on action potential differ from a local...Ch. 11.5 - Prob. 34AYPCh. 11.5 - Prob. 35AYPCh. 11.5 - Prob. 36AYPCh. 11.5 - Prob. 37AYPCh. 11.5 - Prob. 38AYPCh. 11.5 - What is action potential frequency? What two...Ch. 11.5 - Describe sub-threshold threshold, maximal,...Ch. 11.5 - Prob. 41AYPCh. 11.5 - What prevents on action potential from reversing...Ch. 11.5 - Prob. 43AYPCh. 11.5 - Prob. 44AYPCh. 11.5 - Prob. 45AYPCh. 11.6 - What are the components of a synapse? What is the...Ch. 11.6 - What is on electrical synapse? Describe its...Ch. 11.6 - Describe the release of neurotransmitter In a...Ch. 11.6 - Prob. 49AYPCh. 11.6 - Prob. 50AYPCh. 11.6 - Prob. 51AYPCh. 11.6 - Explain the production of EPSPs and IPSPs. Why are...Ch. 11.6 - Prob. 53AYPCh. 11.6 - Prob. 54AYPCh. 11.6 - Prob. 55AYPCh. 11.6 - Prob. 56AYPCh. 11.7 - Diagram a convergent pathway, a divergent pathway,...Ch. 11 - The part of the nervous system that controls...Ch. 11 - Motor neurons and interneurons are _______...Ch. 11 - Cells found in the choroid plexuses that secrete...Ch. 11 - Glial cells that are phagocytic within the central...Ch. 11 - Action potentials are conducted more rapidly In...Ch. 11 - Clusters of neuron cell bodies within the...Ch. 11 - Prob. 7RACCh. 11 - Prob. 8RACCh. 11 - Compared with the inside of the resting plasma...Ch. 11 - Prob. 10RACCh. 11 - Prob. 11RACCh. 11 - If the permeability of the plasma membrane to K+...Ch. 11 - Decreasing the extracellular concentration of K+...Ch. 11 - Prob. 14RACCh. 11 - Which of these statements about ion movement...Ch. 11 - Prob. 16RACCh. 11 - Graded potentials a. spread over the plasma...Ch. 11 - During the depolarization phase of an action...Ch. 11 - Prob. 19RACCh. 11 - Prob. 20RACCh. 11 - Prob. 21RACCh. 11 - Neurotransmitter substances are stored in vesicles...Ch. 11 - In a chemical synapse, Action potentials in the...Ch. 11 - An inhibitory presynaptic neuron can affect a...Ch. 11 - Summation Is caused by combining two or more...Ch. 11 - In convergent pathways. a. the response of the...Ch. 11 - A child eats a whole bottle of salt (NaCl)...Ch. 11 - Prob. 2CTCh. 11 - Prob. 3CTCh. 11 - Prob. 4CTCh. 11 - The speed of action potential propagation and...Ch. 11 - Prob. 6CTCh. 11 - Strychnine blocks receptor sites for inhibitory...Ch. 11 - Prob. 8CTCh. 11 - Prob. 9CTCh. 11 - Prob. 10CT
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- Give two mechanisms by which neurotransmitters exert their effects.arrow_forwardDepression is a condition in which sufferers may feel low mood, lack of motivation and sleep. It is caused by a lack of serotonin in the synaptic cleft of neurone pathways. Serotonin is a neurotransmitter. a) Describe how serotonin acts as a neurotransmitter. Using your understanding of synaptic transmission, explain how communication between neurones in serotonin pathways of the brain would be affected in someone with depression. b) Doctors use tubocurarine drug as an anaesthetic as it temporarily paralyses muscles. It blocks receptors at neuromuscular junctions. Why does this lead to paralysis?arrow_forwardExplain how the binding of heroin to presynaptic neurones raises the probability of action potentials in the postsynaptic neurone. asap typed onlyarrow_forward
- The function of a neurotransmitter is:arrow_forwardWe talked about drug effects on neurons in sequence. The effect of alcohol is multi-faceted and the following question asks you to apply your knowledge. Imagine two neurons in sequence. The presynaptic neuron is GABAnergic and the postsynaptic neuron is dopaminergic. The effects of alcohol are not fully understood but it does seem to inhibit GABAnergic neurons. How would the release of dopamine from the postsynaptic neuron change in this case? Explain your answer, being sure to make each connection between concepts clear. If alcohol instead inhibited dopaminernergic neurons, in what way might the ion flow change in the dendrites of the postsynaptic neuron of this example?arrow_forwardWhich types of patch clamp technique should be used if you want to determine if a particular compound is influencing synaptic transmission presynaptically or post synaptically?arrow_forward
- Identify the multiple mechanisms by which a drug can be pro-ergic or anti-ergic at a synapse.arrow_forwardJohn Hughes and Hans Kosterlitz identified the endorphin receptor in frogs, and concluded that animals have a "built in" opioid system. To make sure that endorphins are truly neurochemicals, which of the following question should we ask these gentlemen? Please select all that apply.a) Are endorphins released in response to presynaptic depolarization? b) Do endorphins interact with postsynaptic receptors? c) Are endorphins found in presynaptic cells? d) Are endorphins subject to reuptake?arrow_forwardExplain the chemical base of neurotransmitter..arrow_forward
- What are the two major classes of neurotransmitter in reference to their effects on postsynaptic cells? How do their modes of action differ? Give an example of each type of neurotransmitter.arrow_forwardDescribe the structural and functional properties of the major classes of neurotransmitters.?arrow_forwardParkinson's Disease Parkinson's disease is neurodegenerative disorder that affects movement. Most people affected with Parkinson's disease demonstrate rigidity, slow movement, and shaking. The symptoms of Parkinson's disease occur when the cells that produce dopamine neurotransmitters die in the brain. Explain how the signal transmission at a synapse in an individual with Parkinson's disease is different than an unaffected individual. Describe the normal process of signal transmission at a synapse. Start with the arrival of an action potential at the axon terminal and include the name of the neurotransmitter that is affected by Parkinson's disease. Explain how the process is different in individuals affected with Parkinson's disease.arrow_forward
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