Explain how the binding of heroin to presynaptic neurones raises the probability of action potentials in the postsynaptic neurone.    asap typed only

The therapeutic effect of Aricept (generic donepezil) is due toA: binding of the drug to voltage-gated sodium channels.C: the drug producing an IPSP on the postsynaptic membrane.D: the drug causing the reuptake of acetylcholine at the synapse.E: the drug maintaining higher concentrations of acetylcholine at synapse

Give two mechanisms by which neurotransmitters exert their effects.

A quanta holds about 10,000 molecules of ACh.  How many quanta are exocytosed during a single presynaptic AP?  What controls or determines the total number of quanta released? Is this under physiological control?

Buckeyium is a medication that binds to the NMDA receptor at the orthosteric binding site (were glutamate would normally bind). Assume glycine is already bonded and magnesium isn't inhibiting the NMDAR ion channel. Buckeyium would be regarded a poison if the channel did not open as a consequence of its binding.

Discuss the mechanisms on how to stop the signal in synaptic transmission.

Which of the following changes would increase serotonin (5-HT) signaling between neurons? Select all that apply; partial point deduction for incorrect choices. O increase in serotonin synthesis O increase in the number of facilitating interneurons O decrease of serotonin receptors in the post-synaptic neuron inhibition of serotonin reuptake transporters O increase in activity of serotonin reuptake transporters O faulty transport and docking of synaptic vesicles decrease in serotonin synthesis O increase of serotonin receptors in the post-synaptic neuron