Concept explainers
To determine: The movement of primase in the lagging strand in figure 11.19.
Introduction: The process of formation of daughter strands from DNA strands is termed as replication of DNA. The enzyme RNA primer initiates the synthesis of daughter DNA strands from the template strand. The RNA primer is synthesized by an enzyme known as DNA primase. Two strands are synthesized by this enzyme. One is the leading strand while the other is the lagging strand.
To determine: Whether primase moves from left to right or from right to left.
Introduction: The process of formation of daughter strands from DNA strands is termed as replication of DNA. The enzyme RNA primer initiates the synthesis of daughter DNA strands from the template strand. The RNA primer is synthesized by an enzyme known as DNA primase. Two strands are synthesized by this enzyme. One is the leading strand while the other is the lagging strand.
To determine: The way in which primase must move after it is done making a primer and has to start making the next primer at a new location.
Introduction: The process of formation of daughter strands from DNA strands is termed as replication of DNA. The enzyme RNA primer initiates the synthesis of daughter DNA strands from the template strand. The RNA primer is synthesized by an enzyme known as DNA primase. Two strands are synthesized by this enzyme. One is the leading strand while the other is the lagging strand.
To determine: Whether primase has to hop from left to right or right to left direction.
Introduction: The process of formation of daughter strands from DNA strands is termed as replication of DNA. The enzyme RNA primer initiates the synthesis of daughter DNA strands from the template strand. The RNA primer is synthesized by an enzyme known as DNA primase. Two strands are synthesized by this enzyme. One is the leading strand while the other is the lagging strand.
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Biology
- Eukaryotic Genetic Sequence: 5'-TAC CAT GAT CCC TAT - 3' 1. What would be the newly synthesized DNA strand and explain how the strand will be replicated. Where in the cell would this occur? 2. What would be the synthesized mRNA strand, and how is it transcribed from the original DNA strand, and then converted from a pre-mRNA strand to a mature mRNA? Where in the cell does this occur? 3. What would be the anti-codons for the tRNA. What are the amino acids generated based on the RNA. How are these amino acids translated into protein and where in the cell does this happen?arrow_forwardDiscuss Concepts During replication, an error uncorrected by proofreading or mismatch repair produces a DNA molecule with a base mismatch at the indicated position: The mismatch results in a mutation. This DNA molecule is received by one of the two daughter cells produced by mitosis. In the next round of replication and division, the mutation appears in only one of the two daughter cells. Develop a hypothesis to explain this observation.arrow_forwardMultiple Replication Forks in E. coli II On the basis of Figure 28.2, draw a simple diagram illustrating replication of the circular E. coli chromosome (a) at an early stage, (b) when one-third completed, (c) when two-thirds completed, and (d) when almost finished, assuming the initiation of replication at oriC has occurred only once. Then, draw a diagram showing the E. coli chromosome in problem 3 where the E. coli cell is dividing every 20 minutes.arrow_forward
- Number of Okazaki Fragments in E. coli and Human DNA Replication Approximately how many Okazaki fragments are synthesized in the course of replicating an E. coli chromosome? How many in replicating an “average� human chromosome?arrow_forwardDo allarrow_forwardMatching Type Choose the directionality of the given process. (4 points) What is the directionality of the given process? * 4 points 3'-5' 5'-3' Exonuclease activity Complementary strand of the continuous strand Addition of nucleotides going to the replication fork Addition of nucleotides away from the replication forkarrow_forward
- Replication:- what other enzymes are involved in the initiation phase?- explain the role of primers in this phase- how is the building of the leading strand different from that of the lagging strand?arrow_forwardQuestion. What would the forward primer sequence look like if it were intended to bind the area of the DNA template?arrow_forwardDNA replication Using the labels below, assign them to the appropriate parts of the diagram.arrow_forward
- Give Detailed explanation Solutionarrow_forwardExplain well please, asaparrow_forwardnand portable. 6.5 mm micro-edge 16405U processon USE YOUR SMARTPHONE w micro-edge display design See dnclamers on product bo Revi Vide Fea Sameness and Variety (Mitosis and Meiosis) 161 Spe Example Sup SCAN Expressed using apples, DNA replication looks like this. Go look at the model of DNA on the demonstration table. We have been presenting DNA as a straight ladder, but actually it is twisted on itself like a spiral staircase. This shape is called a heliz. Observe The Chromosome Normally DNA exists as loose strands (chromatin) in the nucleus of a cell. This nuclear DNA sends a message (RNA) to the ribosomes where protein and enzymes are synthesized. When stretched out, the length of one DNA molecule in a human cell is almost 4 cm. However, the cell itself is but a tiny fraction of that size. During cell reproduction the DNA must be able to move around. So it shortens its length by tightly coiling up. In doing so, the DNA strands become wider and are visible under a microscope.…arrow_forward
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