Campbell Essential Biology with Physiology (6th Edition)
6th Edition
ISBN: 9780134711751
Author: Eric J. Simon, Jean L. Dickey, Jane B. Reece
Publisher: PEARSON
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Textbook Question
Chapter 11, Problem 11SQ
What is the difference between oncogenes and proto-oncogenes? How can one turn into the other? What function do proto-oncogenes serve?
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Chapter 11 Solutions
Campbell Essential Biology with Physiology (6th Edition)
Ch. 11 - Your bone cells, muscle cells, and skin cells look...Ch. 11 - A group of prokaryotic genes with related...Ch. 11 - The regulation of gene expression must be more...Ch. 11 - A eukaryotic gene was inserted into the DNA of a...Ch. 11 - How does dense packing of DNA in chromosomes...Ch. 11 - What evidence demonstrates that differentiated...Ch. 11 - The most common procedure for cloning an animal is...Ch. 11 - What is learned from a DNA microarray?Ch. 11 - Which of the following is a substantial difference...Ch. 11 - Prob. 10SQ
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- How can oncogenes lead to cancer?arrow_forwardProto-oncogenes can change into oncogenes that cause cancer.Which of the following best explains the presence of thesepotential time bombs in eukaryotic cells?(A) Proto-oncogenes first arose from viral infections.(B) Proto-oncogenes are mutant versions of normal genes.(C) Proto-oncogenes are genetic “junk.”(D) Proto-oncogenes normally help regulate cell division.arrow_forwardWhich of the following is an example of a proto-oncogene? 1) cell cycle inhibitor 2) tumor suppressor 3) oncogene 4) repair enzyme 5) growth factor receptorarrow_forward
- How might overexpression of proto-oncogenes lead to abnormal cellular proliferation?arrow_forwardWhat is the experimental evidence that demonstrates direct evidence that chemical carcinogens are able to produce oncogenes?arrow_forwardSuppose a gain-of-function mutation happens in an oncogene. Which of the following changes is likely to result? O a) tumor-promoting inflammation O b) evading growth suppressors Oc) sustaining proliferative signalling O d) resisting cell deatharrow_forward
- Identify two genetic mechanisms whereby proto-oncogenes can become overexpressed. Select the two mechanisms. Identify two genetic mechanisms whereby proto-oncogenes can become overexpressed.Select the two mechanisms. 1) alterations in chromatin structure 2) a gain-of-function alteration 3)modification of proto-oncogenes products 4)mutations that result in an abnormal protein product 5)mutations within gene-regulatory regionsarrow_forwardDescribe the general functions of oncogenes.arrow_forward/20. In class, we discussed diffferent types of genetic change that can cause a normal gene (proto- oncogene) to become a cancer-causing gene (oncogene), Which of the following would not be a cause? A) translocation or transposition (movement of DNA within the same genome) B) gene ampliffication (increased number of copies of a given gene) C) epigenetic change D) point mutation that changes the gene's product E) loss of telomeres during DNA replication ancer?arrow_forward
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