Human Anatomy
9th Edition
ISBN: 9780135168059
Author: Marieb, Elaine Nicpon, Brady, Patricia, Mallatt, Jon
Publisher: Pearson Education, Inc.,
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Chapter 10, Problem 4CRCAQ
Takashi, an osteopathic physician, saw that Mrs. and Mr. Rogers were suffering because their son was fighting a long battle with Duchenne muscular dystrophy. To comfort them, Takashi said that one day physicians hope to be able to cure this disease by injecting healthy myoblasts into the weakened muscles. What are myoblasts?
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2) Paula is a scientist who is developing a drug called Fremtol that will be used to treat muscle spasms. This drug acts on specific skeletal muscles to (1) block the release of Ca2+ ions from the sarcoplasmic reticulum, (2) inhibit the pivoting ability of the myosin heads of the thick filaments, and (3) block the production of ATP by the mitochondria in skeletal muscles. By using this drug, contraction of certain skeletal muscle fibers is reduced, which keeps those muscles from producing spasms.
In the above scenario, Fremtol’s effect of blocking the release of Ca2+ ions from the sarcoplasmic reticulum would most directly prevent which the following?
a. activation of tropomyosin
b. activation of troponin
c. activation of actin
d. All of the above
e. None of the above
3) Paula is a scientist who is developing a drug called Fremtol that will be used to treat muscle spasms. This drug acts on specific skeletal muscles to (1) block the release of Ca2+ ions from the sarcoplasmic reticulum, (2) inhibit the pivoting ability of the myosin heads of the thick filaments, and (3) block the production of ATP by the mitochondria in skeletal muscles. By using this drug, contraction of certain skeletal muscle fibers is reduced, which keeps those muscles from producing spasms.
In the above scenario, Fremtol’s effect of blocking muscle mitochondrial ATP production would result in the inability of the muscle to make ATP from ___________.
a. creatine phosphate
b. anaerobic glycolysis
c. aerobic respiration
d. All of the above
e. None of the above
A) tetany is rapid spasm in the muscle.
B) Tetany is usually caused by an increase in the blood calcium levels.
Write whether statement (B) is correct w.r.t statement (A) ?
Chapter 10 Solutions
Human Anatomy
Ch. 10 - What structural similarities are shared by all...Ch. 10 - Prob. 2CYUCh. 10 - Prob. 3CYUCh. 10 - What are the functional definitions of the origin...Ch. 10 - Place the following structures in order from...Ch. 10 - Which myofilaments are found only in the A band?Ch. 10 - Prob. 7CYUCh. 10 - Prob. 8CYUCh. 10 - Prob. 9CYUCh. 10 - Prob. 10CYU
Ch. 10 - Prob. 11CYUCh. 10 - Prob. 12CYUCh. 10 - Prob. 13CYUCh. 10 - Prob. 14CYUCh. 10 - The connective tissue that lies just outside the...Ch. 10 - Prob. 2RQCh. 10 - Prob. 3RQCh. 10 - Prob. 4RQCh. 10 - Prob. 5RQCh. 10 - Prob. 6RQCh. 10 - Prob. 7RQCh. 10 - Prob. 8RQCh. 10 - Prob. 9RQCh. 10 - Prob. 10RQCh. 10 - Prob. 11RQCh. 10 - Prob. 12RQCh. 10 - Define motor unit.Ch. 10 - List the structural differences between the three...Ch. 10 - Cindy Wong was a good anatomy student, but she...Ch. 10 - Prob. 16RQCh. 10 - Prob. 17RQCh. 10 - Where is titin located, and what are its...Ch. 10 - What is the general distribution of skeletal...Ch. 10 - Prob. 1CRCAQCh. 10 - Prob. 2CRCAQCh. 10 - Chickens are capable of only brief bursts of...Ch. 10 - Takashi, an osteopathic physician, saw that Mrs....Ch. 10 - Why are muscle infections relatively rare...Ch. 10 - As a sprinter, Lateesha knew that the best way to...Ch. 10 - Prob. 7CRCAQCh. 10 - Prob. 8CRCAQCh. 10 - Prob. 9CRCAQ
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- Troponin C has been mutated such that it cannot bind to calcium. Describe the effect of this mutation on sarcomere shortening in skeletal muscle. A complete answer will describe the normal function of troponin C, the normal process of sarcomere shortening, and will describe the overall effect of the mutation on sarcomere shortening based on troponin C's function and its role in the overall process of sarcomere shortening.arrow_forwardWhat is Muscular Dystrophy?arrow_forwardHow does Muscular dystrophy disease affect a common human being?arrow_forward
- An increase in the cross sectional area of muscle is known as hypertrophy. Hypertrophy allows muscle to produce more force due primarily to: a.) Increased number of potential cross bridges that can be formed (i.e., actin-myosin interactions) b.) Increased number of T-Tubules c.) Increased ability to activate the muscle d.) Increased calcium release from the sarcoplasmic reticulumarrow_forwardWith muscular dystrophy, the membrane of muscle cells is destroyed. Given how muscle cells contract, which of the following would fail to happen? Reuptake of acetylcholine by the muscle cells ) Reuptake of acetylcholine by lower motor neurons ) Action potential conduction on muscle cells Action potential conduction on the lower motor neuronsarrow_forward15) what role does calcium play in muscle contraction? a) calcium is not involved in skeletal muscle contraction b) it binds to tropomyosin and moves Tripp in away from the myosin binding sit on the actin molecules c) it's binds to Troponin and moves tropomyosin away from the actin binding sit on the myosin molecules d) it binds to troponin and moves tropomyosin away from the myosin binding site on the actin molearrow_forward
- A 54-year-old patient diagnosed with toxic fume exposure presents with symptoms affecting the neurologic system. On inspection of the upper extremities, you notice small, repetitive local contractions of the muscles visible through the skin. Which of the following best describes these types of abnormal muscle contractions? Answers: A-D A Clonus B Tensus muscularis C Asterixis D Fasciculation Oarrow_forwardA woman is having an extremely prolonged labor. From her anatomy andphysiology course, she remembers the role of Ca2+ in muscle contractionand asks the doctor to give her a Ca2+ injection to speed the delivery.Explain why the doctor would or would not do as she requests.arrow_forwardYou're hiking, you step on a piece of wood and a protruding rusty nail goes right through your Puma Cydes and into your foot. You start thinking....when was my last tetanus booster shot??? We're not talking about tetanus as defined in our studies of muscle physiology, but pathological tetanus (also known as "lockjaw"). In this condition, bacteria called Clostridia tetani (found in dirt) enter the bloodstream and grow, producing tetanus neurotoxin. The result of this toxin coursing through your bloodstream is causes the prime mover and its antagonist muscle groups (doesn't just have to be muscles of the jaw) to contract at the same time. How does the neurotoxin do that? Knowing all this, and being experts on Human reflex Physiology, do you think your reflexes (like the knee-jerk) would still function if you were suffering from "lock-jaw?"arrow_forward
- A patient is thought to be suffering from either muscular dystrophyor myasthenia gravis. How would you distinguish between the twoconditions?arrow_forwardMuscular endurance is defined as the: O a) ability of a muscle to contract repeatedly over an extended period of time b) amount of force a muscle can produce with a single maximal effort O c) ability to move the joints through a full range of motion O d) amount of time required to contract a muscle completelyarrow_forwardMuscular strength is defined as the: a) ability of a muscle to contract with maximal force O b) ability to move the joints through a full range of motion O c) ability to sustain a given level of muscular tension over time d) amount of force a muscle can produce repeatedly over 60 secondsarrow_forward
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