Concepts of Genetics (12th Edition)
12th Edition
ISBN: 9780134604718
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino, Darrell Killian
Publisher: PEARSON
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Chapter 10, Problem 32ESP
Newsdate: March 1, 2030. A unique creature has been discovered during exploration of outer space. Recently, its genetic material has been isolated and analyzed. This material is similar in some ways to DNA in its chemical makeup. It contains in abundance the 4-carbon sugar erythrose and a molar equivalent of phosphate groups. In addition, it contains six nitrogenous bases: adenine (A), guanine (G), thymine (T), cytosine (C), hypoxanthine (H), and xanthine (X). These bases exist in the following relative proportions:
X-ray diffraction studies have established a regularity in the molecule and a constant diameter of about 30 Å. Together, these data have suggested a model for the structure of this molecule.
- (a) Propose a general model of this molecule. Describe it briefly.
- (b) What base-pairing properties must exist for H and for X in the model?
- (c) Given the constant diameter of 30 Å, do you think that either (i) both H and X are purines or both pyrimidines, or (ii) one is a purine and one is a pyrimidine?
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Chapter 10 Solutions
Concepts of Genetics (12th Edition)
Ch. 10 - Would an experiment similar to that performed by...Ch. 10 - In sea urchin DNA, which is double stranded, 17.5...Ch. 10 - German measles results from an infection of the...Ch. 10 - What vital clues were provided by Franklins work...Ch. 10 - Was it ethical for Wilkins to show Franklins...Ch. 10 - Prob. 3CSCh. 10 - HOW DO WE KNOW? In this chapter, we first focused...Ch. 10 - CONCEPT QUESTION Review the Chapter Concepts list...Ch. 10 - Discuss the reasons proteins were generally...Ch. 10 - Contrast the contributions made to an...
Ch. 10 - When Avery and his colleagues had obtained what...Ch. 10 - Why were 32P and 35S chosen for use in the...Ch. 10 - Does the design of the HersheyChase experiment...Ch. 10 - What observations are consistent with the...Ch. 10 - What are the exceptions to the general rule that...Ch. 10 - Draw the chemical structure of the three...Ch. 10 - How are the carbon and nitrogen atoms of the...Ch. 10 - Adenine may also be named 6-amino purine. How...Ch. 10 - Draw the chemical structure of a dinucleotide...Ch. 10 - Describe the various characteristics of the...Ch. 10 - What evidence did Watson and Crick have at their...Ch. 10 - What might Watson and Crick have concluded had...Ch. 10 - How do covalent bonds differ from hydrogen bonds?...Ch. 10 - List three main differences between DNA and RNA.Ch. 10 - What are the three major types of RNA molecules?...Ch. 10 - How is the absorption of ultraviolet light by DNA...Ch. 10 - What is the physical state of DNA after it is...Ch. 10 - What is the hyperchromic effect? How is it...Ch. 10 - Why is Tm related to base composition?Ch. 10 - What is the chemical basis of molecular...Ch. 10 - What did the WatsonCrick model suggest about the...Ch. 10 - A genetics student was asked to draw the chemical...Ch. 10 - Considering the information in this chapter on B-...Ch. 10 - One of the most common spontaneous lesions that...Ch. 10 - In some organisms, cytosine is methylated at...Ch. 10 - Because of its rapid turnaround time, fluorescent...Ch. 10 - Prob. 31ESPCh. 10 - Newsdate: March 1, 2030. A unique creature has...Ch. 10 - During gel electrophoresis, DNA molecules can...Ch. 10 - DNA and RNA are chemically very similar but are...Ch. 10 - Electrophoresis is an extremely useful procedure...
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- In DNA the nucleic acid bases form hydrogen bonds between them, which are responsible for the formation of the double-stranded helix. A hydrogen bond donor is defined as any hydrogen atom that can participate in a hydrogen bond, whereas a hydrogen bond acceptor is defined as any atom that can “receive” that hydrogen atom to form a hydrogen bond. How many hydrogen bond acceptors does guanine (shown below) have? a) 3, b) 5 c) 4 d) 6 e) 7arrow_forwardThe following define nucleic acids EXCEPT A) They are polyionic molecules of high molecular weight composed of subunits or monomers called nucleosides. B) They are chainlike macromolecules that function in the storage and transfer of genetic information. C They are polynucleotides. They contain genes that encode for polypeptides and RNAS.arrow_forwardRNA differs from DNA in that: a) The ribose in RNA nucleotides contains fewer oxygen atoms than does deoxyribose DNA nucleotides. b) It is always single stranded and cannot form base pairs. c) It contains the nucleotide uracil, which pairs with thymine. d) It is single-stranded but can fold into a variety of structures, some of which are double-stranded. e) RNA can only be found in the cytoplasm whereas DNA can only be found in the nucleus.arrow_forward
- Which of the following linkages/bonds is NOT found in the primary structure of DNA and RNA molecules? A phospho anhydride bond B phosphoester bond (c) N-C glycosidic bond phosphodiester bondarrow_forwardDna is composed of a phosphate back bone, a sugar and four nitrogenous bases. Of the following bases: adenine, cytosine, guanine, and thymine; which are the hydrogen bond donors and which are the acceptors?arrow_forwardCells contain two types of nucleic acids: DNA and RNA. Which of the following statements about DNA and RNA is the most accurate? DNA contains uracil whereas RNA contains thymine. All three of the other options are correct. The sugar component of DNA nucleotides contains one less oxygen molecule than is found in the sugar component of RNA nucleotides. Hydrogen bonding can occur between bases in DNA molecules, whereas this does not occur in RNA molecules.arrow_forward
- Which of the following combinations is nucleotide molecule? The nitrogenous base uracil bonded to ribose and phosphate complemented with the addition of a water molecule A nucleoside resulting from the dehydration reaction between two phosphates, glycerol, and an unsaturated fatty acid. The DNA backbone consisting of three phosphate groups, a 5-carbon nitrogenous base, and a nitrogen-containing sugar residue An ATP molecule is formed by combining adenine, ribose, and three inorganic phosphate groupsarrow_forwardA molecule contains adenine, deoxyribose, and one phosphate. Is it a nucleoside or a nucleotide? Would it be found in DNA or RNA?arrow_forwardWhich of the following is cytidine? cytosine + guanine ribose + cytosine + phosphate group ribose + cytosine cytosine + deoxyribosearrow_forward
- Intramolecular ______ are responsible for formation of the most common three-dimensional shape in proteins, the alpha helix. a) van der waals forces b) hydrogen bonds c) covalent bonds d) ionic (electrostatic) interactionsarrow_forwardDehydration synthesis always results in the formation of which of the following? A.)Water B.)Amino acids C.)Proteins D.)Peptidesarrow_forwardRNA differs from DNA in that the base _______________ is substituted for _______________. (a) adenine; uracil (b) uracil; thymine (c) guanine; uracil (d) cytosine; guanine (e) guanine; adeninearrow_forward
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