Becker's World of the Cell (9th Edition)
9th Edition
ISBN: 9780321934925
Author: Jeff Hardin, Gregory Paul Bertoni
Publisher: PEARSON
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Textbook Question
Chapter 10, Problem 10.2CC
Explain how the location and organization of the citric acid cycle enzymes differ from those of the subunits of ATP synthase. How do these differences reflect their different functions?
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What steps of the citric acid cycle are regulated? How and why are they regulated?
What steps in the citric acid cycle are regulated? Why arethey regulated?
give five biological effects of disorders of the citric acid cycle
Chapter 10 Solutions
Becker's World of the Cell (9th Edition)
Ch. 10 - Aerobic respiration uses an external electron...Ch. 10 - Working with 3-D TEM often involves the difficult...Ch. 10 - Explain how the location and organization of the...Ch. 10 - As pyruvate is completely oxidized to CO2 in the...Ch. 10 - Why are the electron carriers in the ETS arranged...Ch. 10 - How is the chemical energy that is released as...Ch. 10 - How does the ATP synthase complex convert the...Ch. 10 - Where do the 38 ATP molecules produced during...Ch. 10 - Localization of Molecules and Functions Within the...Ch. 10 - Localization of Molecules and Functions Within the...
Ch. 10 - True or False. Indicate whether each of the...Ch. 10 - Mitochondrial Transport. For aerobic respiration,...Ch. 10 - Completing the Pathway. In each of the following...Ch. 10 - QUANTITATIVE The Calculating Cell Biologist. Use...Ch. 10 - Prob. 10.7PSCh. 10 - Regulation of Catabolism. Explain the advantage to...Ch. 10 - Lethal Synthesis. The leaves of Dichapetalum...Ch. 10 - QUANTITATIVE Oxidation of Saturated Fatty Acids....Ch. 10 - Oxidation of Cytosolic NADH. In some eukaryotic...Ch. 10 - Brown Fat and Thermogenin. Most newborn mammals,...Ch. 10 - Prob. 10.13PS
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- What is the citric acid cycle? Provide a schematic diagram of the citric acid cycle with chemical structures of each compound in the cycle. Indicate the cofactors and products at each step as well as the name of each of the enzymes involved.arrow_forwardHow are enzymes in Citric Acid Cycle regulated? What are these enzymes and their inhibitors?arrow_forwardWhich reactions of the citric acid cycle transfer energy as FADH2?arrow_forward
- What enzymes from the citric acid cycle that are allosterically regulated by ATP and/or NADH? What enzymes from the citric acid cycle that allosterically regulated by NAD+?arrow_forwardName three enzymes from the citric acid cycle which are allosterically regulated by ATP and/or NADH. Indicate if the binding of these effectors positively or negatively regulate the activity of each of these enzymesarrow_forwardDoes any step of the citric acid cycle directly produce ATP? Explain.arrow_forward
- Discuss the mechanisms of control of the irreversible steps in the citric acid cycle.arrow_forwardVon Gierke’s disease is also known as glycogen storage disease type I. Patients with von Gierke’s disease lackglucose 6-phosphatase activity. Two prominent symptoms of this disorder are fasting hypoglycemia and lactic acidosis (elevated lactate levels in the blood), especially during strenuous exercise. Explain why these symptoms occur. What chemical reaction does this enzyme catalyze? Which pathways involve this enzyme? Lacking thisthe enzyme will cause impairment of which pathways?• Pls consider what pathways are affected by Von Gierke’s disease. Include in your explanation involving Cori’s cycle. can you please do not write by your hand? I mean computer if you can. thank youarrow_forwardVon Gierke’s disease is also known as glycogen storage disease type I. Patients with von Gierke’s disease lackglucose 6-phosphatase activity. Two prominent symptoms of this disorder are fasting hypoglycemia and lactic acidosis (elevated lactate levels in the blood), especially during strenuous exercise. Explain why these symptoms occur. What chemical reaction does this enzyme catalyze? Which pathways involve this enzyme? Lacking thisenzyme will cause impairment of which pathways?• Pls consider what pathways are affected by Von Gierke’s disease. Include in your explanation involving the Cori’s cycle.arrow_forward
- match the cofactor with its function in the citric acid cycle by entering the number corresponding with the function. A given function may be used more than one time or not at all. Use from the following list of functions to fill in the table below: carries O2 carries small carbon-containing molecules carries e- carries small nitrogen-containing molecules Cofactor Function NAD+/NADH FAD/FADH2 CoA thiamine biotinarrow_forwardIdentify at least five biological effects of disorders of the citric acid cyclearrow_forwardThe functioning of a particular pathway often depends not only on control enzymes in that pathway but alsoon control enzymes of other pathways. What happens in the following pathways under the indicated conditions? Suggest what otherpathway or pathways might be influenced.(a) High ATP or NADH concentration and the citric acid cycle.(b) High ATP concentration and glycolysis.(c) High NADPH concentration and the pentose phosphate pathway.(d) High fructose-2,6-bisphosphate concentration and gluconeo genesis.arrow_forward
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