Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN: 9780134580999
Author: Elaine N. Marieb, Katja N. Hoehn
Publisher: PEARSON
Bartleby Related Questions Icon

Related questions

bartleby

Concept explainers

Question
**Question:**

Which **one** of these does CDK1/cyclin mitotic kinase NOT do to induce mitosis?

1. Phosphorylates Histone H1 to condense chromosomes
2. Phosphorylates pore proteins to disassemble pores
3. Phosphorylates transcription factors to shut off transcription
4. Phosphorylates lamins for lamin assembly

This question is testing your knowledge of the specific actions of CDK1/cyclin mitotic kinase and its role in the regulation of mitosis. 

**Detailed Explanation:**

CDK1 (Cyclin-dependent kinase 1), in association with cyclin, plays a vital role in the progression of cells through the cell cycle. During mitosis, CDK1/cyclin complexes have several key functions:

1. **Phosphorylates Histone H1 to condense chromosomes:** This action is crucial for chromatin condensation, which is necessary for the proper segregation of chromosomes during cell division.
   
2. **Phosphorylates pore proteins to disassemble pores:** This refers to the disassembly of the nuclear pore complexes, which is essential for nuclear envelope breakdown, allowing mitotic spindle access to chromosomes.
   
3. **Phosphorylates transcription factors to shut off transcription:** Shutting off transcription during mitosis ensures that resources are focused on cell division rather than gene expression.
   
4. **Phosphorylates lamins for lamin assembly:** This statement is incorrect because CDK1/cyclin actually phosphorylates lamins to disassemble the nuclear lamina, not for lamin assembly. Disassembly of the nuclear lamina is necessary for nuclear envelope breakdown during mitosis.

Hence, the correct answer would be that CDK1/cyclin mitotic kinase does NOT phosphorylate lamins for lamin assembly to induce mitosis.
expand button
Transcribed Image Text:**Question:** Which **one** of these does CDK1/cyclin mitotic kinase NOT do to induce mitosis? 1. Phosphorylates Histone H1 to condense chromosomes 2. Phosphorylates pore proteins to disassemble pores 3. Phosphorylates transcription factors to shut off transcription 4. Phosphorylates lamins for lamin assembly This question is testing your knowledge of the specific actions of CDK1/cyclin mitotic kinase and its role in the regulation of mitosis. **Detailed Explanation:** CDK1 (Cyclin-dependent kinase 1), in association with cyclin, plays a vital role in the progression of cells through the cell cycle. During mitosis, CDK1/cyclin complexes have several key functions: 1. **Phosphorylates Histone H1 to condense chromosomes:** This action is crucial for chromatin condensation, which is necessary for the proper segregation of chromosomes during cell division. 2. **Phosphorylates pore proteins to disassemble pores:** This refers to the disassembly of the nuclear pore complexes, which is essential for nuclear envelope breakdown, allowing mitotic spindle access to chromosomes. 3. **Phosphorylates transcription factors to shut off transcription:** Shutting off transcription during mitosis ensures that resources are focused on cell division rather than gene expression. 4. **Phosphorylates lamins for lamin assembly:** This statement is incorrect because CDK1/cyclin actually phosphorylates lamins to disassemble the nuclear lamina, not for lamin assembly. Disassembly of the nuclear lamina is necessary for nuclear envelope breakdown during mitosis. Hence, the correct answer would be that CDK1/cyclin mitotic kinase does NOT phosphorylate lamins for lamin assembly to induce mitosis.
Expert Solution
Check Mark
Knowledge Booster
Background pattern image
Biology
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.
Similar questions
Recommended textbooks for you
Text book image
Human Anatomy & Physiology (11th Edition)
Biology
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:PEARSON
Text book image
Biology 2e
Biology
ISBN:9781947172517
Author:Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:OpenStax
Text book image
Anatomy & Physiology
Biology
ISBN:9781259398629
Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:Mcgraw Hill Education,
Text book image
Molecular Biology of the Cell (Sixth Edition)
Biology
ISBN:9780815344322
Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher:W. W. Norton & Company
Text book image
Laboratory Manual For Human Anatomy & Physiology
Biology
ISBN:9781260159363
Author:Martin, Terry R., Prentice-craver, Cynthia
Publisher:McGraw-Hill Publishing Co.
Text book image
Inquiry Into Life (16th Edition)
Biology
ISBN:9781260231700
Author:Sylvia S. Mader, Michael Windelspecht
Publisher:McGraw Hill Education