What is the role of FAD in the preparation of pyruvate to enter the citric acid cycle? to perform a decarboxylation to eliminate a NADH group to perform an oxidation to regenerate the disulfide bond in lipoamide to perform a reduction to regenerate the disulfide bond in lipoamide to perform a hydrolysis to eliminate a NADH group
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What is the role of FAD in the preparation of pyruvate to enter the citric acid cycle?
- to perform a decarboxylation to eliminate a NADH group
- to perform an oxidation to regenerate the disulfide bond in lipoamide
- to perform a reduction to regenerate the disulfide bond in lipoamide
- to perform a hydrolysis to eliminate a NADH group
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- Complete oxidation of a 16-carbon fatty acid can yield 129 molecules of ATP Study Figure 19.2 and determine how many ATP molecules would be generated if a 16-carbon fatly acid were metabolized solely by the TCA cycle, in the form of S acetyl-CoA molecules.Based on your knowledge of the structure of NAD+ and an assumption that coenzyme dissociation is the rate limiting step of the alcohol dehydrogenase mechanism, hypothesize why a N249W mutation at the coenzyme binding site would increase the rate of catalysis.After the citric acid cycle reactions run _________, one six-carbon glucose molecule has been completely broken down to CO2. a. once b. twice c. six times d. twelve times
- What steps in the citric acid cycle have each of the following characteristics? a. The reaction generates FADH 2. b. The organic substrate is oxidized. c. The reaction utilizes NAD +. d. The reaction breaks a carbon–carbon bond.Which of the following molecules shown are the reduced products produced in the citric acid cycle whose reduction directly helped drive oxidation? Select all that apply. Ensure you are selecting the product forms of the molecule, which here means the reduced form, and are only considering redox reactions! Do not include the pyruvate processing steps -- just the citric acid cycle itself. A. GDP B. NADH C. FAD D. Acetyl-CoA E. NAD+ F. CoA G. FADH2 H. GTP I. QH2 J. QList four products of glycolysis. How is pyruvate modified before entering the citric acid cycle? Why is the citric acid cycle called a cycle?
- Which of the following reactions DOES NOT take place during the citric acid cycle? The energy investment phase, whereby two phosphates are added to glucose to make Fructose-1,6-biphosphate. The hydrolysis of fumarate to make malate. FAD retrieves hydrogen ions and electrons from succinate to form FADH2 and fumarate. Carbon dioxide is released when alpha-ketoglutarate is transformed to Succinyl CoA.Which of the following is the third step of Citric Acid Cycle? Select one: a. Succinyl-CoA becomes Succinate and forms one ATP molecule and Coenzyme A-SH b. Pyruvate is decarboxylated to become acetyl-CoA producing NADH and Carbon dioxide c. Isocitrate and then decarboxylated and oxidized to produce alpha-ketoglutarate, Carbon dioxide and NADH d. alpha-ketoglutarate is oxidized and decarboxylated to produce Succinyl-CoA, Carbon dioxide and NADH e. Succinate is oxidized to become fumarate forming FADH2 f. Oxaloacetate combines with the acetyl from acetyl-CoA to produce Citric acid(citrate) g. Citrate is rearranged to become Isocitrate h. Malate is oxidized to become oxaloacetate forming NADH i. Fumarate is combined with water to become MalateWhat is the first cofactor to accept electrons from pyruvate in the Pyruvate dehydrogenase complex? Thymine pyroposphate lipoyllysine FAD NAD⁺
- Which of the following is the second step of Citric Acid Cycle? Select one: a. Isocitrate and then decarboxylated and oxidized to produce alpha-ketoglutarate, Carbon dioxide and NADH b. Succinyl-CoA becomes Succinate and forms one ATP molecule and Coenzyme A-SH c. alpha-ketoglutarate is oxidized and decarboxylated to produce Succinyl-CoA, Carbon dioxide and NADH d. Malate is oxidized to become oxaloacetate forming NADH e. Fumarate is combined with water to become Malate f. Citrate is rearranged to become Isocitrate g. Pyruvate is decarboxylated to become acetyl-CoA producing NADH and Carbon dioxide h. Oxaloacetate combines with the acetyl from acetyl-CoA to produce Citric acid(citrate) i. Succinate is oxidized to become fumarate forming FADH2How does each of the following regulate citric acid cycle?(a) High levels of Succinyl-CoA(b) High levels of ADP(c) High levels of NADHThe citric acid cycle is shown. The methyl carbon in acetyl CoA is labeled with C14C14 (shown in red). Identify which of the carbons in each intermediate will be labeled in the first round of the cycle by selecting the indicated carbon(s). Each question has multiple options except citrate. Which carbon in citrate will contain C14? 4 1 3 2 Which carbon(s) in isocitrate will contain C14? 1 2 3 4 5 6 Which carbon(s) in α‑ketoglutarate will contain C14? 1 2 3 4 5 Which carbon(s) in succinyl‑CoA will contain C14? 1 2 3 4 Which carbon(s) in succinate will contain C14? 1 2 3 4 Which carbon(s) in fumarate will contain C14? 1 2 3 4 Which carbon(s) in malate will contain C14? 1 2 3 4 Which carbon(s) in oxaloacetate will contain C14? 1 2 3 4