Biochemistry
9th Edition
ISBN: 9781319114671
Author: Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher: W. H. Freeman
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- Pyruvate + NAD+ + CoA → Acetyl COA NAIDHI + H + CO₂ This is the overall reaction for the pathway of Glycolysis Oxidative decarboxylation of pyruvate Fatty acid oxidation Ellectron transport Oxidative phosphorylation TCA or citric acid cyclearrow_forwardAcetyl CoA 00-COA COA Six -carbon molecule formed from acetyl CoA + oxaloacetate Four-carbon acceptor molecule (regenerated in each cycle) O00000 Citrate One carbon lost as 5 co2 O000 Oxaloacetate NAD+ NADH NADH + CO2 NAD* Secand carbon NAD+ lost as COz NADH + COD Reduced electron carrier similar to NADH Z7 GDP, O FADH2 Energy-carrying n molecule equivalent FAD GTP to ATParrow_forwardAlpha-ketoglutarate dehydrogenase exhibits feedback inhibition byarrow_forward
- Which of the following glycolytic enzymes catalyzes the conversion of fructose-1,6-bisphosphate into the two product molecules dihydroxyacetone phosphate, and glyceraldehyde-3-phosphate? phosphoglycerate kinase pyruvate kinase malate dehydrogenase aldolase phosphofructokinasearrow_forwardWhich of the following statements is true for the shown reactions? Deficiency of oxaloacetate stimulates the formation of X and y Insulin signaling stimulates the formation of X and Y Both A and B Neither A nor Barrow_forwardWhich citric acid cycle enzyme utilizes a similar reaction mechanism to pyruvate dehydrogenase? O Malate dehydrogenase Isocitrate dehydrogenase O Alpha-ketoglutarate dehydrogenase Succinate dehydrogenasearrow_forward
- The following reaction, the last reaction in beta-oxidation, is an example of a: Enzyme Enzyme-H S-CoA S-COA H2C H3C CoA s–CoA C H2 CH2 R S-COA S-COA S-COA O A. Nucleophilic acyl substitution O B. Electrophilic addition OC. Nucleophilic addition D. Aldol condensation O E. Hydrohalogenationarrow_forwardUnder anaerobic conditions, following the radiolabel at carbon-2 of pyruvate, in which molecule does the carbon label ultimately end up so that it can be taken up by the muscle cell and used for metabolism? Lactate C-2 Glucose C-2 and C-5 Acetyl- CoA C-2 Glucose C-1 and C-6 CO2 Pyruvate C-2arrow_forward[References) Which of the following statements explains why acetyl-CoA Iis considered the central molecule of metabolism? (Select all that apply.) O The addition of acetyl-CoA to compounds stabilises them. Acetyl-CoA contains a thioester bond that makes it one of the high energy compounds in metabolic pathways. O Acetyl-CoA is an inhibitor that plays a central role in regulating metabolic pathways. O Acetyl-CoA feeds directly into the citric acid cycle. U None of the above.arrow_forward
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