Which of the following vitamins do you expect to enter the cell via diffusion (i.e., NOT need a transporter?) A C B НО НО ОН. D HO NH₂ ОН ОН

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
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**Title: Vitamin Diffusion and Cellular Entry**

**Question:**
Which of the following vitamins do you expect to enter the cell via diffusion (i.e., NOT need a transporter)?

**Image Description:**
The image contains chemical structures labeled A, B, C, and D, representing different vitamins:

- **A:** This chemical structure displays a long, nonpolar, hydrocarbon chain with a ring structure at the end. It appears to be a lipid-soluble vitamin due to its extended hydrophobic chain.

- **B:** This structure contains multiple hydroxyl (OH) groups, suggesting a polar and possibly water-soluble vitamin. It has a ring structure with an additional carboxylic acid group.

- **C:** Displays a ring structure including nitrogen atoms, with a hydrogen-bonding capable group attached which indicates some degree of polarity.

- **D:** This structure includes multiple nitrogen atoms in a heterocyclic ring and potentially polar functional groups.

**Explanation:**
Understanding whether a vitamin can enter the cell via simple diffusion depends largely on its polarity and solubility:

- **Lipid-Soluble Vitamins:** Likely to diffuse across the lipid bilayer of the membrane. These are typically nonpolar.
  
- **Water-Soluble Vitamins:** Usually require transporters to cross cell membranes due to their polarity.

From the structures provided, structure **A** would most likely enter the cell via diffusion because it appears to be nonpolar and lipid-soluble. Structures **B, C, and D** are more polar, suggesting they may require transporters to cross the cell membrane.
Transcribed Image Text:**Title: Vitamin Diffusion and Cellular Entry** **Question:** Which of the following vitamins do you expect to enter the cell via diffusion (i.e., NOT need a transporter)? **Image Description:** The image contains chemical structures labeled A, B, C, and D, representing different vitamins: - **A:** This chemical structure displays a long, nonpolar, hydrocarbon chain with a ring structure at the end. It appears to be a lipid-soluble vitamin due to its extended hydrophobic chain. - **B:** This structure contains multiple hydroxyl (OH) groups, suggesting a polar and possibly water-soluble vitamin. It has a ring structure with an additional carboxylic acid group. - **C:** Displays a ring structure including nitrogen atoms, with a hydrogen-bonding capable group attached which indicates some degree of polarity. - **D:** This structure includes multiple nitrogen atoms in a heterocyclic ring and potentially polar functional groups. **Explanation:** Understanding whether a vitamin can enter the cell via simple diffusion depends largely on its polarity and solubility: - **Lipid-Soluble Vitamins:** Likely to diffuse across the lipid bilayer of the membrane. These are typically nonpolar. - **Water-Soluble Vitamins:** Usually require transporters to cross cell membranes due to their polarity. From the structures provided, structure **A** would most likely enter the cell via diffusion because it appears to be nonpolar and lipid-soluble. Structures **B, C, and D** are more polar, suggesting they may require transporters to cross the cell membrane.
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