This pedigree depicts the inheritance of the mitochondrial disease Leber hereditary optic neuropathy (LHON). Individual I-1 does not show any symptoms of LHON, whereas her daughter and all three of her grandchildren are affected. Provide two explanations for this.

Q: ase within a family. Square symbols represent males and circle symbols represent females. Dark…

A: Autosomal recessive

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Q: inheritance of a mutation that causes the mitochondrial disease MERFF.

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Q: Why do the muscles of facial expression move the skin ratherthan a joint?

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A: Introduction  Galactosemia is the autosomal recessive disorder. The affected individual is unable to…

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Mitochondrial Mutations

A mitochondrion is a cellular organelle that serves as the site for cellular respiration and energy production (ATP or Adenosine Triphosphate). It is a double-membrane-bound organelle and is only present in eukaryotic cells.