Predict the consequence if presynaptic action potentials in an axonrelease insufficient acetylcholine to depolarize a skeletal muscle fiber tothreshold.
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Predict the consequence if presynaptic action potentials in an axon
release insufficient acetylcholine to depolarize a skeletal muscle fiber to
threshold.
Step by step
Solved in 2 steps
- High blood K+ concentrations cause depolarization of the restingmembrane potential. Predict and explain the effect of high blood K+levels on smooth muscle functionIdentify the steps that show how an action potentialproduced in the motor end-plate of the neuromuscularjunction eventually results in contraction of the muscle fiber.Rising of REM in endplate potential of skeletal muscle fiber by chemical stimulation to threshold point . Discuss all event for that
- Explain how more than one smooth muscle cell can be influenced by an action potential generated in an autonomic postganglionic nerve terminalProvide a explantion and diagram of the Intracellular mechanism of smooth muscle relaxation via antagonists such as atropine binding and blocking muscarinic receptors M3. explain how Atropine blocks the acetylcholine receptorsBoth the withdrawal reflex and the Golgi tendon reflex involve sensory signals that ultimately control the same type ofmotor neurons and both are protective. Explain how one reflex can cause muscle contraction while the other causes musclerelaxation.
- Define what the NMJ is and why it's important for muscle contraction. Explain in short the process of the NMJ signaling the muscle to contract. Note the difference between a motor unit and the NMJ.List and describe the events that take place (and the structuresinvolved) between excitation of the skeletal muscle cellmembrane by an action potential and the initiation of cross-bridge action.Explain the intracellular mechansim of smooth muscle relaxation of agaonist such as mepyrimine and atropine. Give diagram for each.
- Explain in detail cholinergic/acetylcholine receptors and what role they plain in Smooth muscle contraction. Provide intraceullar mechanism.If a single twitch of a skeletal muscle fiber lasts 40 msec, what action potential stimulation frequency (in action potentials per second) must be exceeded to produce an unfused tetanus?Explain how optimal skeletal muscle force (high muscle tension) can be achieved during a high intensity exercise. (Mention and explain how wave summation, motor recruitment summation, muscle length, and type of muscle fibers activated can affect muscle force).