.The poison ouabain (wah-BAY-in), or arrow poison, blocks the Na+ K+pump. What effect would this poison have on the sodium and potassium ion gradients and so on the action potentials of a muscle fiber?
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.The poison ouabain (wah-BAY-in), or arrow poison, blocks the Na+ K+pump. What effect would this poison have on the sodium and potassium ion gradients and so on the action potentials of a muscle fiber?
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- High blood K+ concentrations cause depolarization of the restingmembrane potential. Predict and explain the effect of high blood K+levels on smooth muscle functionDefine what the NMJ is and why it's important for muscle contraction. Explain in short the process of the NMJ signaling the muscle to contract. Note the difference between a motor unit and the NMJ.Give an account of the excitation-contraction coupling (Figure 3) in skeletal muscle fibers. Highlight the role of dihydropyridine receptors and ryanodine receptors and the fate of A detailed description of the cross bridge cycle is not calcium ions after contraction. necessary. -Axon teminal of (=) somatic motor neuron ACh Muscle fiber potential Pion ++ Action potential- Na Motor end plate- T-tubule Sarcoptasmic reticulum lellll Ca2+ DHP receptor Tropomyosin Troponin z disk Actin M line Myosin head Myosin thick filament
- Explain in detail how the of relaxion towards Smooth muscle contraction is done by the antagonsists atropine and mepyramine. Provide intracelluar mechanism of relaxation.The endplate potential decreases with distance because too spread Na* channels the muscle membrane is too thin the leakiness of the muscle fiber the accumulation of voltage-gated channels none of the aboveSkeletal muscle is described as striated. What are the lighter, thinner stripes noted under the microscope? Group of answer choices troponin actin myosin dystrophin Rather than innervating individual muscle fibers, motor neurons often innervate two or more muscle fibers. The motor neuron and the muscle fibers it innervates are together called a: Group of answer choices motor unit myofibril muscle fascicle motor fascia Fast glycolytic muscle fibers allow for relatively quick ATP energy production by splitting glucose (but eventually leads to fatigue), a process described as: Group of answer choices fermentation aerobic pathway anaerobic pathway ATP reserve use
- Put these events that occur in skeletal muscle in the correct chronological sequence: 1. Activation of voltage-gated dihydropyridine (DHP) receptor in the T-tubule 2. Opening of mechanically-gated ryanodine receptors (RyR) on the sarcoplasmic reticulum 3. Na+ influx through ligand-gated ion channels on the motor end plate 4. Ca2+ binding to troponin 2, 1, 4, 3 4, 3, 2, 1 4, 3, 1, 2 3, 1, 4, 2 3, 1, 2, 4a. Define threshold potential. b. One student commented that the threshold potential for this muscle fibre is exactly 50 mV. Do you agree or disagree? Why or why not?Explain how the process of skeletal muscle excitation–contraction coupling demonstrates the general principle of physiology that controlled exchange of materials occurs between compartments and across cellular membranes.
- Rising of REM in endplate potential of skeletal muscle fiber by chemical stimulation to threshold point. Discuss all event lead for that.Match the following regarding muscle contractions: The final chemical messenger and "trigger" for muscle contraction. It binds to troponin A neurotransmitter released at motor end plates by the axon terminals It diffuses across the cell membrane resulting in depolarization Activates synaptic vesicles in axon terminals to fuse with plasma membrane of axon terminal Used to convert ADP to ATP by transfer of a high-energy phosphate group. A reserve high-energy compound Breaks down ACh into its building blocks, rendering it ineffective [Choose] [Choose] [Choose] [Choose] [Choose] [Choose ]Discuss the following statement: “The basal lam-ina of muscle fibers serves as a molecular bulletin board,in which adjoining cells can post messages that direct thedifferentiation and function of the underlying cells.”