Neuroactive drugs, such as the antidepressant fluoxetine, function by affecting the metabolism of the brain. After the neurotransmitter serotonin has crossed the syrupse and attached to the post- synaptic neuron, the serotonin is normally reabsorbed by the pre-synaptic neuron. Fluoxetine inhibits the reuptake of serotonin. allowing it to remain in the synapse much longer than normal A Synapse O a. Z Ob. Y с. Х W- Fluoxetine inhibits the process above labelled... Nerve impulse

Concerning neurons, DESCRIBE how local anaesthetics prevent the propagation of an Action Potential.

The monoamine hypothesis of depression proposes that monoamine oxidase is overproduced in very depressed people. O depression is a result of low monoamine levels at synapses. depression is a result of high monoamine levels at synapses. monoamine oxidase is absent in very depressed people.

Parkinson's disease causes tremors and slow movement due to the brain's inability to produce enough dopamine. Thus, to treat Parkinson's, doctors would MOST likely prescribe a dopamine: efferent. agonist. antagonist.

Imagine that a new type of psychoactive drug has been developed in a laboratory. It works by slowing the reuptake of dopamine in some brain circuits, increasing the amount of dopamine in the synapse. It also blocks serotonin binding in other brain circuits. Based on only this information, you can conclude that this new psychoactive drug is a: dopamine and serotonin antagonist. dopamine antagonist and serotonin agonist. dopamine and serotonin agonist. dopamine agonist and serotonin antagonist.

Explain the mechanism by which action potentials are prevented from being propagated to a postsynaptic cell if transmitted across an inhibitory synapse.

discuss the excitatory NMDA receptor, the role of the Mg++ ion, and how NMDA activation can produce Long Term Potentiation (which could underlie memory). Finally, what is the seemingly unique involvement of neighboring glia cells in helping to regulate both GABA and Glutamate neurotransmission and why might that glia cell role occur

Drugs called selective serotonin reuptake inhibitors (SSRIs) affect the reuptake of neurotransmitter by presynaptic cells. SSRIs are used for the treatment of depression.  Serotonin normally causes an excitatory postsynaptic potential. Explain why neurotransmitter reuptake is important.  And describe what effect the SSRI would have on the response of these postsynaptic cells and why.

Which of the following is the role of axonal Calcium (Ca2+) channels in neuronal communication at the synapse? a) they inhibit the action potential causing it to stop b) Calcium channels have no role in this process c) by allowing calcium to exit the cell, they promote the propagation of action potential across the synapse by creating depolarization d) by blocking calcium entrance, they mediate the contraction of presynaptic axon to facilitate movement e) when they open, calcium enters the presynaptic terminal, promoting fusion of neurotransmitter vesicles with presynaptic membrane, and release of neurotransmitters to the synaptic cleft

Synaptogenesis is involved in long term memory consolidation. Describe the ways new synapses could form.