In some cases, people who suffer from depression can be prescribed a serotonin re-uptake inhibitor if they are determined to be resistant to behavioral treatment. Explain how a serotonin re-uptake inhibitor would alter concentrations of serotonin in the brain.  Would this change occur at all synapses within the brain? Why or why not?

What is the most likely mechanism producing tolerance to cocaine and then the dysphoria that is associated with cocaine withdrawal?   A. Dynorphin neurons cause presynaptic inhibition to decrease dopamine release into the nucleus accumbens   B. Cocaine runs the dopamine transporter backwards to cause tolerance and withdrawal   C. cocaine binds to opiate receptors in the ventral tegmental area (VTA)   D. Dynorphin neurons stimulate dopamine neurons in the ventral tegmental area (VTA) and increase dopamine release into the nucleus accumbens

Which receptors are the main source of inhibition in the brain? To what ions are they permeable? Describe how those receptors mediate shunting inhibition.

Describe the 5 basic steps of electrical and chemical neural signaling.  A strong action will explain each step.  Also, describe at least one way synaptic connections can change as a result of experience or learning.