If you inhibit the closing of sodium channels what do you predict the effect on neuronal function will be? If you inhibit the closing of sodium channels what do you predict the effect on neuronal function will be? Hyper-excitability: more sodium ions flow into the cell, causing neurons to fire more readily Hypo-excitability: more sodium ions flow into the cell, causing neurons not to fire as readily Less sodium is pumped out of the cell, slowing down return to the resting state Sodium ions are toxic to neurons, leading to cell proliferation

If you inhibit the closing of sodium channels what do you predict the effect on neuronal function will be? If you inhibit the closing of sodium channels what do you predict the effect on neuronal function will be? Hyper-excitability: more sodium ions flow into the cell, causing neurons to fire more readily Hypo-excitability: more sodium ions flow into the cell, causing neurons not to fire as readily Less sodium is pumped out of the cell, slowing down return to the resting state Sodium ions are toxic to neurons, leading to cell proliferation

Biology 2e

2nd Edition

ISBN:9781947172517

Author:Matthew Douglas, Jung Choi, Mary Ann Clark

Publisher:Matthew Douglas, Jung Choi, Mary Ann Clark

Chapter35: The Nervous System

Section: Chapter Questions

Problem 2VCQ: Figure 35.11 Potassium channel blockers, such as amiodarone and procainamide, which are used to...

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Action potentials occur when ______. a. potassium gates close b. a stimulus pushes membrane potential to threshold c. sodium-potassium pumps become active d. neurotransmitter is reabsorbed
If a potassium channel is held open for even longer, leading to an even bigger hyperpolarization of the cell what will happen in an afferent neuron? action potentials will have a larger amplitude action potentials will have a small amplitude less frequent action potentials in the neuron more frequent action potentials in the neuron
You can choose one or more than one option About neuronal excitability, what are the correct statements? Neurons communicate via action potential and synapses The action potential is characterized by the rapid inversion of the membrane potential from negative to positive values Synaptic vesicles contain neurotransmitters that are secreted in a calcium-dependent process Ligand-gated neurotransmitter receptors are membrane protein ion channels Voltage-gated potassium channels are responsible for the depolarization phase of the action potential
Which of the following is FALSE about action potentials? At resting potential, there are more potassium channels open and most sodium channels are closed. Depolarization is due to the flow of Na+ out of the axon via voltage-gated Na+ channels. Hyperpolarization is due to continued loss of K+ from the axon. During repolarization, K+ flows out of the axon along its concentration gradient. Resting membrane potential is primarily established by the Na+/K+ pump.
Which of the following phases of an action potential is correctly matched with the changes in ion movement and membrane potential? All of these are correctly matched. Phase 1 – sodium movement into the cell Phase 3 – potassium movement into the cell Phase 2 – sodium movement out of the cell
During the resting state, a neuron is: polarized with sodium ions outside the cell and potassium ions inside the cell restoring the ionic conditions utilizing the sodium-potassium pump depolarizing and generating an action potential propagating the action potential repolarizing as potassium ions diffuse out of the cell
An action potential is regarded as an example of positive feedback. Which of the following examples below best illustrates the positive feedback aspect of an action potential? Voltage gated potassium ion channels open slowly and remain open long enough to cause hyperpolarization The sodium potassium pump consistently moves ions as long as ATP is available, and regardless of membrane potential changes. A threshold stimulus will cause the opening of voltage gated sodium ion channels that will cause further depolarization by opening still more voltage gated sodium ion channels along the axon.
- Which of the following describes the concentration of K+ and Na+ ions in and around a resting neuron?1- K+ and Na+ ion concentrations are both higher outside of the cell.2- K+ ion concentration is higher inside of the cell, Na+ ion concentration is higher outside of the cell.3- K+ ion concentration is higher outside of the cell, Na+ ion concentration is higher inside of the cell.4- K+ and Na+ ion concentrations are similar inside of and outside of the cell. - An action potential:1- is a large change in polarization.2- is an "all-or-nothing" response.3- will travel down the length of the axon4- all of the above - What prevents action potentials from traveling away from synaptic terminals?1- Inactivation of Na+ channels behind the zone of depolarization.2- Inactivation of K+ channels behind the zone of depolarization.3- An increased in graded potential along the length of the axon.4- All of the above - Which brain region is incorrectly paired with one of its functions?1- midbrain -…
Which of the following does NOT contribute to the establishment or maintenance of the neuron resting membrane potential? Oa sodium and potassium ions are actively transported across the cell membrane which maintains the resting membrane potential Ob. negatively charged proteins are inside the neuron and are not transported out Oc potassium ions are highly concentrated outside the cell and their are many potassium leakage channels in the membrane Od. sodium ions are more highly concentrated outside the cell and there are fewer sodium ion leakage channels in the membrane
What causes Hyperpolarization following the spike of the action potential? Voltage-gated K+ channels close slowly allowing K+ ions to leave the cell The opening of leaky Na+ channels The Na+/K+ pump briefly reverses the direction of ion flow Both Na+ channels and K+ channels become inactivated Na+ and Cl- enter the cell until the Na+/Cl- pump closes
Based upon the changes in permeability seen in the trace below and your knowledge of ion distributions across a cell, predict how ion movements would change during an action potential. Drag and drop each phrase into the appropriate box on the action potential trace. Drag the appropriate labels to their respective targets. Note: not all labels will be used. ►View Available Hint(s) Sodium (Na+) ions move to the axon Sodium (Na) ions move out of the axon Less potassium (K) ions move out of the axon Potassium (K) ions move out of the axon Potassium (K¹) ions move into the axon Sodium (Na) ions stop moving in Membrane potential (mv) +30 +10 0 -10- -30 -50 -70 -90 A PNa 0 PNa 5 6 1 PK Threshold PK 2 Reset Help
Match each type of membrane potential to its definition: The membrane potential at which voltage gated sodium channels open. The membrane potential that triggers the action potential. Threshold potential Change in membrane potential that may or may not reach threshold and that may be depolarizing or hyperpolarizing. Rapid, strong depolarization followed by immediate repolarization. This potential is self-renewing if the right ion channels are nearby. Answer Options: Resting Potential, Threshold Potential, Graded Potential, Action Potential