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How would azithromycin influence quorum sensing in this bacterium?
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- How would someone design an experiment to test the role of azithromycin on quorum sensing in Pseudomonas aeruginosa?What advantage do quorum-sensing systems confer onbacterial cells?Under cellular conditions, dATP can be oxidized to its 2-hydroxy form, which is a substrate for an enzyme that converts 2-OH-dATP to 2-OH-dAMP + PPi. Explain why compounds that inhibit the activity of this enzyme would be eff ective anticancer agents.
- Why might bacteria use quorum sensing to regulate genes needed for virulence? How might this reason be related to the rationale behind using quorum sensing to establish a symbiotic relationship?What does the two component signal transduction system allow cells to do? What are the two components and what do they do? How was this type of system used in Streptococcus pneumoniae transformation?If you isolate a bacteria from the digestive system system of mouse, what would you expect the bacterial response to varying pH to be? What would you likely classify this bacteria as?
- Which statement among A-D is false regarding bacterial toxins? A) O Hemolysıns are cell membrane disrupters that can rupture red blood cells. B) O Second mesengar pathway disrupters like cholera toxin produces a debilitating respiratory condition of the lungs. C) O Shiga toxin, tetanus toxin, and hemolysins are all types of exotoxins. D) O Superantigens elicit a hyperactive response by the immune system and can lead to shock. E) O None are false, A-D are all true statements.Which bacterial type ( Gram positive or Gram negative) is more sensitive to the antibiotic penicillin? Explain why?What is the practical implication of exponential growth in bacteria?