Answered: Genomic DNA was isolated from three…

Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

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Genomic DNA was isolated from three individuals shown in the pedigree above. Primers were used to amplify DNA sequences at a particular locus using PCR and the DNA was resolved by gel electrophoresis. The result is presented in Figure I. What can we conclude from the gel patterns about which band corresponds to which allele (HINT: think dominant/recessive)? (3 sentences minimum)

III IV
V
VII OTVI
Figure 1: Family pedigree tracing a genetic
disease.
Individual Individual Individual
I
II
III
Origin
Larger Fragments
Smaller Fragments
Figure II: Image of a gel
electrophoresis of DNA fragments from
the same gene obtained from 3
individuals in the above pedigree.

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