Following the analysis of a pedigree, a genetic link at 4cM is considered between a mutation leading to a pathology and the molecular marker HUMTH01. The study counts 14 "parental" and 3 "recombinant" individuals. We call p(theta=0.04) is the probability of obtaining such a pedigree in case of a 4cM genetic linkage, p(theta=0.5) is the probability of obtaining such a pedigree in case of independence between the mutation and the marker, Z(theta=0.04) the value of the Lod-score under the assumption of 4cM genetic linkage. Tick all the correct answers: Op(theta=0,04)=1,79.10E-9 and Z(theta=0,04)=0,47 Op(theta=0,5)=7,18.10E-12 p(theta=0,04)=2,75.10E-10 and Z(theta=0,04)=0,77 and Z(theta=0,04)=0,67 and Z(theta=0,04)=0,47 Op(theta=0,5)=6,04.10E-10 Op(theta=0,5) = 9,36.10E-12 and Z(theta=0,04)=1,33 Op(theta =0,5)=5,82.10E-11 and Z(theta=0,04)=0,67 no correct answer Op(theta=0,04)=4,31.10E-11 Op(theta=0,04)=2,01.10E-10 and Z(theta=0,04)=0,77 and Z(theta=0,04)=1,33

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
icon
Related questions
Topic Video
Question
Following the analysis of a pedigree, a genetic link at 4cM is considered between a mutation leading to a pathology and the molecular marker HUMTH01. The
study counts 14 "parental" and 3 "recombinant" individuals. We call p(theta=0.04) is the probability of obtaining such a pedigree in case of a 4cM genetic
linkage, p(theta=0.5) is the probability of obtaining such a pedigree in case of independence between the mutation and the marker, Z(theta=0.04) the value of
the Lod-score under the assumption of 4cM genetic linkage. Tick all the correct answers:
p(theta=0,04)=1,79.10E-9 and Z(theta=0,04)=0,47
p(theta=0,5)=7,18.10E-12
and Z(theta=0,04)=0,77
and Z(theta=0,04)=0,67
p(theta=0,04)=2,75.10E-10
p(theta=0,5)=6,04.10E-10 and Z(theta=0,04)=0,47
p(theta=0,5)=9,36.10E-12 and Z(theta=0,04)=1,33
p(theta =0,5)=5,82.10E-11 and Z(theta=0,04)=0,67
no correct answer
p(theta=0,04)=4,31.10E-11
p(theta=0,04)=2,01.10E-10
and Z(theta=0,04)=0,77
and Z(theta=0,04)=1,33
Transcribed Image Text:Following the analysis of a pedigree, a genetic link at 4cM is considered between a mutation leading to a pathology and the molecular marker HUMTH01. The study counts 14 "parental" and 3 "recombinant" individuals. We call p(theta=0.04) is the probability of obtaining such a pedigree in case of a 4cM genetic linkage, p(theta=0.5) is the probability of obtaining such a pedigree in case of independence between the mutation and the marker, Z(theta=0.04) the value of the Lod-score under the assumption of 4cM genetic linkage. Tick all the correct answers: p(theta=0,04)=1,79.10E-9 and Z(theta=0,04)=0,47 p(theta=0,5)=7,18.10E-12 and Z(theta=0,04)=0,77 and Z(theta=0,04)=0,67 p(theta=0,04)=2,75.10E-10 p(theta=0,5)=6,04.10E-10 and Z(theta=0,04)=0,47 p(theta=0,5)=9,36.10E-12 and Z(theta=0,04)=1,33 p(theta =0,5)=5,82.10E-11 and Z(theta=0,04)=0,67 no correct answer p(theta=0,04)=4,31.10E-11 p(theta=0,04)=2,01.10E-10 and Z(theta=0,04)=0,77 and Z(theta=0,04)=1,33
Expert Solution
steps

Step by step

Solved in 3 steps

Blurred answer
Knowledge Booster
Patterns of inheritance
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.
Similar questions
  • SEE MORE QUESTIONS
Recommended textbooks for you
Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
Biology
ISBN:
9780134580999
Author:
Elaine N. Marieb, Katja N. Hoehn
Publisher:
PEARSON
Biology 2e
Biology 2e
Biology
ISBN:
9781947172517
Author:
Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:
OpenStax
Anatomy & Physiology
Anatomy & Physiology
Biology
ISBN:
9781259398629
Author:
McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:
Mcgraw Hill Education,
Molecular Biology of the Cell (Sixth Edition)
Molecular Biology of the Cell (Sixth Edition)
Biology
ISBN:
9780815344322
Author:
Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher:
W. W. Norton & Company
Laboratory Manual For Human Anatomy & Physiology
Laboratory Manual For Human Anatomy & Physiology
Biology
ISBN:
9781260159363
Author:
Martin, Terry R., Prentice-craver, Cynthia
Publisher:
McGraw-Hill Publishing Co.
Inquiry Into Life (16th Edition)
Inquiry Into Life (16th Edition)
Biology
ISBN:
9781260231700
Author:
Sylvia S. Mader, Michael Windelspecht
Publisher:
McGraw Hill Education