Explain why people with type AB+ blood can receive blood transfusions from any blood type, but people with O- blood can ONLY receive blood from O- donors. What type of white blood cells would cause an immune reaction if the wrong type of blood was used?
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- In terms of antigens and antibodies, explain why O- is considered a universal donor and why AB+ is considered a universal recipient. Even so, why can’t whole blood O- be donated to a person of type AB+ blood?Select all the statements below that are true regarding hemolytic disease of the newborn. If a mother is Rh- and becomes sensitized with anti-Rh antibodies, all subsequent children will be affected Hemolytic disease of the newborn can only occur if the mother is Rh-. If an Rh- mother becomes sensitized, only her subsequent children with Rh+ blood will be affected If a mother is Rh- and her first child is Rh+, the child's RBCS will be attacked by the mother's antibodies.You have a patient with prostate cancer. The cancer causes blood vessels to weaken and burst. The patient has a dangerously low Hematocrit and needs a blood transfusion. When you test his blood for type, here are the results: Anti-A- agglutination, Anti-B- agglutination, Anti-Rh- no reaction. 1. List all blood types he can receive. When you enthusiastically suggest that blood transfusions will help him, he protests that his religious beliefs disallow him from accepting transfusions. You will need to find a way to help his own body both retain the blood he has, and make new blood. 2. Based only on what we've learned so far re: blood and endocrine, come up with hypotheses about how you could do each. 3. Propose a mechanism of how EPO might work: what cells might it target, would it enter them, and what sorts of proteins might it activate? (This question references endocrine: how hormones work, and why it matters if they are water-soluble or fat-solube) 4. There is a drug called…
- BC, a 25-year-old African American female, has presented to the emergency department at a local hospital with severe vaginal bleeding. She is 17 weeks pregnant. This is her first pregnancy and she has no history of transfusion or transplantation. Specimens have been drawn for laboratory testing, including an order for a type and antibody detection test. What is BC's Rh type? Forward Typing Reverse Typing Anti-A Anti-B Anti-D A1 Cells B Cells 4+ 0 0 0 4+ Question 2 options: A) Further testing should be done to confirm Rh. B) D+ C) Weak D+ D) D-Fill in the following table. Blood type Antigens on red blood cells Antibodies in plasma Type A+ Type A - Type B + Type B - Type AB + Type AB - Type O + Type O -You mix a few drops of a patient’s blood with ABO and Rh typing serums (antibodies against A, B, and Rh antigens), with these results: Anti-A: agglutination; Anti-B: no agglutination; Anti-Rh: agglutination. What is the patient’s ABO blood group and Rh type? A positive O negative O positive AB negative A negative
- If transplanting a solid organ such as a kidney, why is MHC II matching also important to success of the graft?A person with type O Rh+ blood would have Group of answer choices No antigens and a, b, & d antibodies D antibodies and A & B antigens D antigens and a and b antibodies A, B, & D antigens and no antibodies Which of the following makes platelets stick to collagen to form a plug? Group of answer choices Heparin Plasmin Fibrin von Willenbrand factorThere is a variety of organs routinely transplanted in clinical medicine. Knowing that organ transplantation is routinely performed in clinic answer the following: What is a significance of HLA-typing used to match with the most suitable recipient? What has been achieved by using powerful immunosuppressive drugs?
- When a mother is Rh-, there is a chance the baby may have hemolytic disease of Newborns. Rh+ mothers do not have this issue. Why? Rh- moms do not have the Rh antigen in their body. A Rh- mom can have a Rh+ baby depending on the male sperm. During pregnancy, Rh- mom can be exposed to her baby's Rh antigen. Let's look at figure a) the first pregnancy. The Rh- mom is pregnant with a Rh+ baby. The baby exposes the mom to Rh antigen during pregnancy. This first baby is delivered and is ok. Figure (b) between pregnancies, the mother is exposed to the foreign antigen Rh and she makes antibodies against Rh. She now has anti-D (anti-Rh) in her body. Figure (c) her second pregnancy with a Rh+ baby. On the next pregnancy that the mom has with a baby. The mom has the anti-D (anti-Rh) antibody in her system. The antibody will attack the baby's RBCS with the Rh antigen on it. When the baby's RBC's are attacked the RBC will hemolyse (hemo=RBC; Lysis=cut). This will result in severe anemia. The lysed…Choose all the correct statments. A person with type AB blood can receive a transfusion form a type O individual. A person with type O blood can receive a transfusion from a type AB individual. A person with only the A antigen on the surface of red blood cells is type A. They also have anti B antibodies in their plasma. A person with antigens A and B on the surface of their red blood cells is type AB and have no antibodies in their plasma. A person with the Rh factor is Rh+. A person who is type O has the O antigen on the surface of their red blood cells, and have anti A antibodies in their plasma.You are solving for an unknown blood type. Drops of blood have been mixed with solutions containing the antibodies Anti- A, Anti-B and Anti-Rh. The test results are are pictured below. Using your knowledge of antibody- antigen interactions and the principle of agglutination, identify the blood type and answer the associated questions