When a mother is Rh-, there is a chance the baby may have hemolytic disease of Newborns. Rh+mothers do not have this issue.Why? Rh- moms do not have the Rh antigen in their body. A Rh- mom can have a Rh+ babydepending on the male sperm. During pregnancy, Rh- mom can be exposed to her baby's Rhantigen.Let's look at figure a) the first pregnancy. The Rh- mom is pregnant with a Rh+ baby. The babyexposes the mom to Rh antigen during pregnancy. This first baby is delivered and is ok.Figure (b) between pregnancies, the mother is exposed to the foreign antigen Rh and she makesantibodies against Rh. She now has anti-D (anti-Rh) in her body.Figure (c) her second pregnancy with a Rh+ baby. On the next pregnancy that the mom has with ababy. The mom has the anti-D (anti-Rh) antibody in her system. The antibody will attack thebaby's RBCS with the Rh antigen on it.When the baby's RBC's are attacked the RBC will hemolyse (hemo=RBC; Lysis=cut). This willresult in severe anemia. The lysed RBC will release high levels of bilirubin causing potential toxicbrain syndrome.We have ways of preventing this from happening now. All Rh- mom's are given a shot at 26-28weeks of pregnancy and with 72 hours of delivery. The RhoGAM will bind to the fetal RBC's Rhantigen and "cover" it up, so the mom's body does not t make anti-D antibody.Checkyour knowledge:1) Which pregnancy should you give mom the RhoGAM Wh? Every, because you do not want the mom tomake Anti-D18-22

Red blood cells of each individual have different antigens on the surface. Some have A antigen, some…

Answered: 1) Which pregnancy should you give mom…

Science

Biology

1) Which pregnancy should you give mom the RhoGAM Wh? Even, because vou do not want the mom to make Anti-D 18-22

Concepts of Biology

1st Edition

ISBN:9781938168116

Author:Samantha Fowler, Rebecca Roush, James Wise

Publisher:Samantha Fowler, Rebecca Roush, James Wise

Chapter17: The Immune System And Disease

Section: Chapter Questions

Problem 3ACQ: Figure 17.17 The Rh antigen is found on Rh-positive red blood cells. An Rh-negative female can...

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Question

When a mother is Rh-, there is a chance the baby may have hemolytic disease of Newborns. Rh+
mothers do not have this issue.
Why? Rh- moms do not have the Rh antigen in their body. A Rh- mom can have a Rh+ baby
depending on the male sperm. During pregnancy, Rh- mom can be exposed to her baby's Rh
antigen.
Let's look at figure a) the first pregnancy. The Rh- mom is pregnant with a Rh+ baby. The baby
exposes the mom to Rh antigen during pregnancy. This first baby is delivered and is ok.
Figure (b) between pregnancies, the mother is exposed to the foreign antigen Rh and she makes
antibodies against Rh. She now has anti-D (anti-Rh) in her body.
Figure (c) her second pregnancy with a Rh+ baby. On the next pregnancy that the mom has with a
baby. The mom has the anti-D (anti-Rh) antibody in her system. The antibody will attack the
baby's RBCS with the Rh antigen on it.
When the baby's RBC's are attacked the RBC will hemolyse (hemo=RBC; Lysis=cut). This will
result in severe anemia. The lysed RBC will release high levels of bilirubin causing potential toxic
brain syndrome.
We have ways of preventing this from happening now. All Rh- mom's are given a shot at 26-28
weeks of pregnancy and with 72 hours of delivery. The RhoGAM will bind to the fetal RBC's Rh
antigen and "cover" it up, so the mom's body does not t make anti-D antibody.
Check
your knowledge:
1) Which pregnancy should you give mom the RhoGAM Wh? Every, because you do not want the mom to
make Anti-D
18-22

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