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- Identify the multiple mechanisms by which a drug can be pro-ergic or anti-ergic at a synapse.Name and discuss the function of 2 common neurotransmitters.Small-molecule neurotransmitters include all the following types, except :-a- Substance Pb- gamma amino butyric acidc- acetylcholined- norepinephrine
- True or False: 4) Symptoms of withdrawal are usually the opposite of the effects of the previously used drug. 5) Although their main effects occur in other neurochemical systems, both MDMA (Ecstasy) and cannabis distort the activity of dopamine, suggesting that these drugs have the potential to be addictive. 6) Opioids produce most of their effects by enhancing the release of a variety of neurochemicals from presynaptic axon terminals.What are the two major classes of neurotransmitter in reference to their effects on postsynaptic cells? How do their modes of action differ? Give an example of each type of neurotransmitter.Give FOUR criteria for identifying a substance as a neurotransmitter.
- a)Explain how the presynaptic cell "knows" when to release its neurotransmitter into the synaptic cleft. b)Explain the difference between excitatory and inhibitory neurotransmitters in regards to their effect on the postsynaptic cell.There are a broad range of anti-epileptic medications currently on the market, with different therapies prescribed for different types and severities of the condition. Given what you have learned about synaptic transmission, which of the following could be a potential therapeutic approach to prevent the spreading of neuronal excitation? (3 correct answers, select all that apply) O A voltage-gated calcium channel blocker/inhibitor selective to glutamate-releasing neurons. O A voltage-gated calcium channel blocker/inhibitor selective to GABA-releasing neurons. O A glutamate receptor blocker (antagonist). O A GABA receptor antagonist. O A glutamate reuptake inhibitor. O A GABA reuptake inhibitor.Discuss Presynaptic factors?