Complete the Table Precision of the weighing balance Weight of the empty beaker 0.0001 g 25.0330 g Volume capacity and precision of the volumetric 1000 ml; P=0.01 ml flask Concentration of the solution 0.10 M Volume of the solution Weight of the beaker+ CSP (Cupric Sulfate Pentahydrate) Weight of the CSP (Cupric Sulfate Pentahydrate)
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- Nernst (equilibrium) Potential (mV) - 6.lol 0.07 0.125 D.094 lon Intracellular Extracellular Concentration (mM) Concentration (mM) K* 155 4 Nat 12 145 Ca** 104 1.5 4 120 D) If during the generation of an action potential in the skeletal muscle cell the membrane potential approaches +65 mV, membrane permeability for which ion likely plays a major role in membrane depolarization? Explain your choice.The ion flows across neuronal membranes at rest and duringan action potential do not significantly change bulk ionconcentrations, except for that of Ca2+ ions. Resting Ca2+ ionconcentrations in cells are usually about 10–7 M, and Ca2+ ionsexert physiological effects at concentrations of perhaps 10–5 M.Explain why relative changes of intracellular [Ca2+] are muchgreater than for, say, [Na+] (12–50 mM).Myasthenia gravis is a disease that leads to a marked decrease in the number of acetylcholine (Ach) receptors at the neuromuscular junction. As a result, suppose only about 200 (instead of 2000) Ach receptor-channels are opened by each quantum of Ach. The Ach-gated channels that survive operate normally and each cause a depolarization of about 0.25 x 10-3 mV when open. The function of the presynaptic terminal is normal and an action potential will cause the release of 100 quanta of neurotransmitter. For a patient with myasthenia gravis, what would be the magnitude of the depolarization (in mV) associated with opening of one Ach-gated channel? a.) 0.25x10^-2 mv b.) 0.25x10^-3 mv c.) 0.25x10^-4 mv d.) 0.5x10^-1 mv e.) 0.5 mv
- Myasthenia gravis is a disease that leads to a marked decrease in the number of acetylcholine (Ach) receptors at the neuromuscular junction. As a result, suppose only about 200 (instead of 2000) Ach receptor-channels are opened by each quantum of Ach. The Ach-gated channels that survive operate normally and each cause a depolarization of about 0.25 x 10-3 mV when open. The function of the presynaptic terminal is normal and an action potential will cause the release of 100 quanta of neurotransmitter. Part a.) For a patient with myasthenia gravis, what would be the size (in mV) of a miniature excitatory post-synaptic potential (or that associated with one quantum of Ach)? a.) 0.05 mv b.) 0.25x10-4 mv c.) 0.25x10-3 mv d.) 0.5x10-3 mv e.) 0.5 mv Part b.) For a patient with myasthenia gravis, what would be the size (in mV) of the full excitatory post synaptic potential consequent to the entry of an action potential into the presynaptic terminal of the neuromuscular junction? a.) 70 mv…Table Q1(a) shows typical values for the intracellular and extracellular concentrations of the major ion species (in millimoles per litre) for frog skeletal muscle. Table Q1(a) Permeability (cm/s) 2 x 10-8 2х 10 Ions Intracellular Extracellular Na* 12 145 K+ 155 4 4 120 4 x 106 By referring to Table Q1(a), compute the equilibrium resting potential for this membrane by assuming the room temperature is 20° C. Given the Boltzman's constant, k = 1.38 x 1023 J/K and an electronic charge, q = 1.602 x 10-19 C.(a) Table Q1(a) shows typical values for the intracellular and extracellular concentrations of the major ion species (in millimoles per litre) for frog skeletal Q1 muscle. Table Q1(a) Permeability (cm/s) 2 x 10-8 2 x 106 4 x 10-6 Ions Intracellular Extracellular Na* 12 145 K* 155 4 4 120 By referring to Table Q1(a), compute the equilibrium resting potential for this membrane by assuming the room temperature is 20° C. Given the Boltzman's constant, k= 1.38 x 1023 J/K and an electronic charge, q = 1.602 x 1019 C.
- Remaining Time: 1 hour, 16 minutes, 05 seconds. Qu B BIUS Paragraph V Arial P 田 心田 V 10pt X2 X2 # A = K7 ヒン V V V A V V T +] ABC V r T " Π 99 Ω € + QUESTION 27 What is the correct time-span for each stage in the "information processing model"? For each of the stages (sensory, short-term, and long- term), choose letter A, B, or C. Sensory Long-term memory Short-term (or working) memory A. Days to Years B. 1-2 seconds C. 30 seconds to several minutes QUESTION 28 Which one below does not describe the meaning of "episodic memory? This refers to remembering events and experiences at specific times and places. This refers to remembering the sequence of events and when things happened.Calculate the free energy of transport for the movement of potassium by the sodium/potassium pump under normal physiological conditions: 4 mM serum potassium, 135 mM intracellular potassium, 37.1 °C, and resting potential -82 mV. Express your answer in kJ/mol. Show all work. Calculate the free energy of transport for the movement of potassium by the sodium/potassium pump under disturbed conditions of 2 mM serum potassium. Assume all other parameters remain the same. Express your answer in kJ/mol. Show all work. What factors could limit the continued action of the sodium/potassium pump when only 2 mM potassium is present in the blood plasma? Note that under normal physiological conditions, the cell interior contains 11 mM sodium and the blood contains 140 mM sodium.35.Given the following table, calculate the Resting Membrane Potential (in mV, rounded to the nearest tenths), using the GHK equation. Ion [Outside] mM [Inside] mM Relative Permeability at Rest Nernst Potential (mV) K+ 4 130 1.0 -110.2 Na+ 130 5 0.04 67.4 Cl- 75 5 0.45 -97.5
- Reducing the saline [Cl-] from 550 mM to 350 mM resulted in a change in the reversal potential of a crustacean muscle IPSP from -66 mV to -55 mV. Resting potential remained unchanged at -60 mV. What can you deduce about the ionic mechanisms of the IPSP?The resting membrane potential of a neuron at 37°C is –60 mV (inside negative). If the freeenergy change associated with the transport of Na+ from o utside to in side is –10.0 kJ/mol, and [Na+]outside the cell is 260 mM, what is [Na+] inside the cell?gas constant R=8.315 J/mol.K; Faraday constant F=96.5 kJ/mol.voltThe order in the MAR is for Atropine 15 mg IV q6h hours PRN. How many mL will you give if the dosage strength is 75mg/7.5mL?
