3-1. For each of the given amino acids, write the equilib- rium reactions that would apply at a pH corresponding to each of the pK, values for each amino acid: (a) alanine; (b) glutamic acid; (c) arginine; (d) a₁, e-diaminopimelic acid (pK₁, = 1.8, pK₁₂ = 2.2, pKa, = 8.8, pK, = 9.9), whose for- a4 mula is HOOCCH(CH,) CHCOOH 1..... NH₂ NH₂

3-1. For each of the given amino acids, write the equilib- rium reactions that would apply at a pH corresponding to each of the pK, values for each amino acid: (a) alanine; (b) glutamic acid; (c) arginine; (d) a₁, e-diaminopimelic acid (pK₁, = 1.8, pK₁₂ = 2.2, pKa, = 8.8, pK, = 9.9), whose for- a4 mula is HOOCCH(CH,) CHCOOH 1..... NH₂ NH₂

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

See similar textbooks

Similar questions

Chemistry Given TETRAPEPTIDE: Prolinyl-Argininyl-Cysteinyl-Tryptophan Predict the direction of the peptide in electrophoresis at pH 7 and pH11.5. (Use table on the upper right for the estimated pK values of some functional groups).
Calculate pI for arginine (pKa (carboxyl) = 3.1; pKa (amino) = 8.0; and pKa (R group) = 12.5
Do
On the paper provided, draw the chemical structure of a peptide with a sequence YIQV at pH 14. The pKa value of the Y sidechain is 10.1.
Lys - Glu - His - Arg - Ile Which statement is FALSE: (a) At low pH, the amino terminal has a charge of +1. (b) At low pH, Glu has charge 0. (c) At high pH, the carboxyl terminal has a negative charge. (d) At high pH, His has a charge of -1. (e) At pH 7, Arg has a charge of +1. At high pH, the charge on the peptide is: (a) -2 (b)-1 (c) 0 (d) +1 (e) +2
The isoelectric point (pl) can best be calculated by: Averaging the sums of all pkas. Averaging the sum of the two pKas closest to physiological pH. Averaging the two pKas "sandwiching" the zwitterionic form. Averaging the two pKas of the alpha-amino and alpha-carboxy groups.
Calculate the average charge of the peptide KLMRDCP (pKa = 3.5, 3.9, 8.3, 9.5, 10.0, 12.5) at pH 7.40.
Draw a structural formula for the form of amino acid most prevalent at pH 1.0. (a) Arginine
Calculate the percentage ionization (i.e. [base]/[acid]x100) in these amino acid side chains at the pH values specified (show your work for one of these amino acid chains): - Aspartate (pKa=4.1) at pH 5.4 - Arginine (pKa=12.5) at pH 11.8 - Histidine (pKa=6.0) at pH 8.0 - Tyrosine (pKa=10.9) at pH 8.0
(A) How many peptide bonds are present in peptide 1? (B) What is the N-terminal amino acid in peptide 2? (C) What is the C-terminal amino acid in peptide 2?
Draw a tetra peptide of Ser-His-Leu-Tyr at pH=1
The reaction of methane with fluorine is highly explosive. Using bond dissociation energies and the Lewis structures, determine the NET energy change for the reaction CH4 + 2 F2 → C + 4 HF.