would chymotrypsin to be most active at a pH of 4.5, 7.8, or 10.0?

Calculate the % of the Tyrosine side chains that are deprotonated at pH 10.8.

The carbon-nitrogen peptide bond is rigid, but rotation can take place about the N-C, and the Co-C bonds in a protein (Co is the a carbon atom). These bond angles define the conformation of the peptide chain. Consider the Ramachandran plot to answer both questions. Which observation most likely describes part of an observed a helix? = −60°; y = −47°; many Ala residues -59°; y = +150°; many Ser residues -57°; y = -47°; many Pro residues -140°; y = +130°; many Val residues +60°; y = +40°; many Gly residues Φ $ = Φ $ = = = (degrees) 180 120 60 O -60 -120 -180 -180 0 (degrees) 180

Guanidine and the guanidino group present in arginine are two of the strongest organic bases known. Account for their basicity.