Chemistry
Chemistry
10th Edition
ISBN: 9781305957404
Author: Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher: Cengage Learning
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You have a peptide with the sequence HEEDRKYYLCG.
You may assume that the side-chain pKa values from the textbook are correct for the peptide.
You may further assume that, for any pH more than 2 pH units away from the pKa value, the
group will be fully protonated or deprotonated.
a) What is the charge on the peptide at pH 1?
b) What is the charge on the peptide at pH 6?
c) What is the charge on the peptide at pH 12.5?
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Transcribed Image Text:You have a peptide with the sequence HEEDRKYYLCG. You may assume that the side-chain pKa values from the textbook are correct for the peptide. You may further assume that, for any pH more than 2 pH units away from the pKa value, the group will be fully protonated or deprotonated. a) What is the charge on the peptide at pH 1? b) What is the charge on the peptide at pH 6? c) What is the charge on the peptide at pH 12.5?
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