Genetic Analysis: An Integrated Approach (3rd Edition)
3rd Edition
ISBN: 9780134605173
Author: Mark F. Sanders, John L. Bowman
Publisher: PEARSON
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Chapter E, Problem 2P
Compare and constast the terms paternity index (PI) and combined paternity index (CPI). How does each contribute to paternity determination?
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Write brief summaries (no longer than three lines) on each of the following topics:(what/why/advantage(s)/disadvantage(s)) Manchester-specific markers
Show the complete solution including the Punnett Sq. Lina has dimples, freckles, and a widow’s peak. She is a heterozygous for all of the three traits. David, her husband also has freckles and dimples but has a continuous hairline. As freckle is known to be dominant over none, dimples are dominant over no dimples, and widow’s peak is dominant over continuous hairline, identify the
Probability that their child will have three recessiveness: no freckle, no dimples, and has widow’s peak; and
Probability that their child will have the same phenotype as Lina (with freckles, dimples, and widow’s peak).
Legend:
Ff – freckles
Dd – dimples
Ww – widow’s peak
How do I fill out the chart and find the probability?
Chapter E Solutions
Genetic Analysis: An Integrated Approach (3rd Edition)
Ch. E - E.1 What is CODIS? Describe the four most...Ch. E - Compare and constast the terms paternity index...Ch. E - What is exclusion principle? How is it used in...Ch. E - What is the statistical principle underlying...Ch. E - Explain the meaning of identity by descent in the...Ch. E - Prob. 6PCh. E - E.7 The results shown are from a DNA test for four...Ch. E - E.8 Figure illustrates the results of an...Ch. E - E.9 Additional STR allele frequency information...Ch. E - Prob. 10P
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- Hemophilia is inherited as a sex-linked recessive trait. A non-hemophilic man marries a non-hemophilic woman whose father had hemophilia. With respect to this information, indicate all possible genotypes their children could possibly have. Show ALL work using punnett squares.arrow_forwardWhat is the assignment is to provide definitions of the following five terms? A. Homozygous genotype (or homozygote) B. Heterozygous genotype (or heterozygote)arrow_forwardFor the following Chi-square table, how many degrees of freedom should be used when calculating the p-value? Gender Phenotype O E O-E (O-E)2 (O-E)2/E Male Disease 99 101.5 -2.5 6.25 0.061576 WT 105 101.5 3.5 12.25 0.12096 Female Disease 0 0 0 0 0 WT 202 203 -1 1 0.004926 Total 406 406 19.5 0.187192 You do not need to know the degrees of freedom to calculate the p-value. a. 4 b. 5 c. 2 d. 3arrow_forward
- The following is a summary of the possible sickle-cell genotypes and phenotypes: AA - cojmpletely normal AS - sickle-cell trait (this person has a combination of normal hemoglobin and the abnormal, sickled form of hemoglobin) SS - sickle-cell anemia (all abnormal hemoglobin) Make a punnett square for help answering the question: What is the probability of a couple having a child with sickle-cell trait if one parent is normal and the other has sickle-cell trait?arrow_forwardA) A husband and wife have four daughters. What is the probability that their fifth child will also be a girl? B) Six children are born on the same day. What is the probability that three will be boys and three will be girls? please show work. thanksarrow_forwardShow the complete solution including the Punnett Sq. Lina has dimples, freckles, and a widow’s peak. She is a heterozygous for all of the three traits. David, her husband also has freckles and dimples but has a continuous hairline. As freckle is known to be dominant over none, dimples are dominant over no dimples, and widow’s peak is dominant over continuous hairline, what is the a) Probability that their child will have three recessiveness: no freckle, no dimples, and has widow’s peak; and b) Probability that their child will have the same phenotype as Lina (with freckles, dimples, and widow’s peak)? Legend: Ff – freckles Dd – dimples Ww – widow’s peakarrow_forward
- What will be the possible offspring from a dad who has hemophilia and a mom who is a carrier? Include Punnett square, genotypic and phenotypic ratios.arrow_forwardUnder what conditions does one expect a 1:1:1:1 ratio?arrow_forwardWhat is the probability of passing on a Genetic disorder( as a percentage)arrow_forward
- The identity of Kim's biological father is unknown, but it is thought to be either Kevin or Thomas. To determine which of the two men it is, blood typing of all the persons involved was performed. Here are the results of the blood tests, including the phenotypes and possible genotypes of each person: Rachel (mother) Type AB; genotype IA, IB Kim (child) Type A; genotype is either IA, IA (if homozygous) or IA, i (if heterozygous) Kevin (alleged father #1) Type A; genotype is either IA,IA if homozygous or IA, i if heterozygous Thomas (alleged father #2) Type O; genotype is ii There are 2 DNA bands in the "fingerprint" of each person tested: mother, child, alleged father 1, and alleged father 2. Why are there two bands for each person and not three?arrow_forwardUsing the two equations, p + q = 1 and p2 + 2pq + q2 = 1, answer the following question A Hispanic-American couple wants to know their risk for having a child with cystic fibrosis. One parent has no family history of disease, but the other parent has a sibling with cystic fibrosis. Calculate the conditional probability that the couple has a child with cystic fibrosis.arrow_forwardWhat is the genotypic ratioarrow_forward
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