Genetic Analysis: An Integrated Approach (3rd Edition)
3rd Edition
ISBN: 9780134605173
Author: Mark F. Sanders, John L. Bowman
Publisher: PEARSON
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Chapter E, Problem 13P
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Disease name: Chronic myelogenous leukemia (CML)
1. Outline the processes of the best DNA technology tools/techniques involved in the diagnosis of the disease
2. Present the best therapeutic DNA technology tool/technique for the disease by describing the tool and discussing the procedure
3. Identify the challenges or issues that a scientist may face for using the DNA technology diagnostic and therapeutic tools and application
Manufacturers of self-contained test kits apply for and receive Food and Drug Administration (FDA) approval for their particular test to be on the Clinical Laboratory Improvement Amendment (CLIA) waived list. To find out if your particular brand of self-contained test kit is on the CLIA waived list, access an up-to-date listing at the FDA website(https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfclia/analyteswaived.cfm (Links to an external site.)) and use the key search term “Currently Waived Analytes” (be forewarned, though, that the list is very long) (Cited from Chap. 37).
Research the link to the FDA to find your kit name on the list.
Discuss the following questions:
Why would it be important to have this kit listed here?
Can a POL use kits that are not listed?
Topic:
Recombinant pharmaceuticals (for the production of insulin, human growth hormone or blood clotting factors)
Questions:
Give a research scientist (not a company) who laid the foundation for this process OR is currently working in an area involving this process.
Chapter E Solutions
Genetic Analysis: An Integrated Approach (3rd Edition)
Ch. E - E.1 What is CODIS? Describe the four most...Ch. E - Compare and constast the terms paternity index...Ch. E - What is exclusion principle? How is it used in...Ch. E - What is the statistical principle underlying...Ch. E - Explain the meaning of identity by descent in the...Ch. E - Prob. 6PCh. E - E.7 The results shown are from a DNA test for four...Ch. E - E.8 Figure illustrates the results of an...Ch. E - E.9 Additional STR allele frequency information...Ch. E - Prob. 10P
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