Concepts of Genetics (12th Edition)
12th Edition
ISBN: 9780134604718
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino, Darrell Killian
Publisher: PEARSON
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Chapter 8, Problem 3NST
What is the effect of a rare double crossover (a) within a chromosome segment that is heterozygous for a pericentric inversion; and (b) within a segment that is heterozygous for a paracentric inversion?
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a)
Explain why when a chiasma is formed, only 50% of the meiotic products will be of
recombinant type.
b)
Determine the sequence of the three genes (y, cl and vg) that are linked on a chromosome
based on the genetic distances provided below:
y- vg
43
y- cl
vg – cl
5
38
Progeny of triploid tomato plants often contain parts of an extra chromosome, in addition to the normal complement of 24 chromosomes (J. W. Lesley and M. M. Lesley. 1929. Genetics 14:321–336). Mutants with a part of an extra chromosome are referred to as secondaries. James and Margaret Lesley observed that secondaries arise from triploid (3 n), trisomic (3 n + 1), and double trisomic (3 n + 1 + 1) parents, but never from diploids (2 n). Give one or more possible reasons that secondaries arise from parents that have unpaired chromosomes but not from parents that are normal diploids.
In Figure 17-19, is there any difference between the inversion products formed from breakage and thoseformed from crossing over?
Chapter 8 Solutions
Concepts of Genetics (12th Edition)
Ch. 8 - A human female with Turner syndrome (47, X) also...Ch. 8 - When two plants belonging to the same genus but...Ch. 8 - What is the effect of a rare double crossover (a)...Ch. 8 - Controlling the overgrowth of invasive aquatic...Ch. 8 - Controlling the overgrowth of invasive aquatic...Ch. 8 - Controlling the overgrowth of invasive aquatic...Ch. 8 - HOW DO WE KNOW? In this chapter, we have focused...Ch. 8 - Review the Chapter Concepts list on page 171....Ch. 8 - Define these pairs of terms, and distinguish...Ch. 8 - For a species with a diploid number of 18,...
Ch. 8 - What evidence suggests that Down syndrome is more...Ch. 8 - What evidence indicates that humans with aneuploid...Ch. 8 - Contrast the fertility of an allotetraploid with...Ch. 8 - Describe the origin of cultivated American cotton.Ch. 8 - Predict how the synaptic configurations of...Ch. 8 - Inversions are said to suppress crossing over. Is...Ch. 8 - Contrast the genetic composition of gametes...Ch. 8 - Human adult hemoglobin is a tetramer containing...Ch. 8 - Discuss Ohnos hypothesis on the role of gene...Ch. 8 - What roles have inversions and translocations...Ch. 8 - The primrose, Primula kewensis, has 36 chromosomes...Ch. 8 - Certain varieties of chrysanthemums contain 18,...Ch. 8 - Drosophila may be monosomic for chromosome 4, yet...Ch. 8 - Mendelian ratios are modified in crosses involving...Ch. 8 - Having correctly established the F2 ratio in...Ch. 8 - The mutations called bobbed in Drosophila result...Ch. 8 - The outcome of a single crossover between...Ch. 8 - A couple planning their family are aware that...Ch. 8 - In a cross in Drosophila, a female heterozygous...Ch. 8 - A woman who sought genetic counseling is found to...Ch. 8 - Prob. 25ESPCh. 8 - In a recent cytogenetic study on 1021 cases of...Ch. 8 - A boy with Klinefelter syndrome (47,XXY) is born...Ch. 8 - Prob. 28ESPCh. 8 - A 3-year-old child exhibited some early indication...Ch. 8 - A normal female is discovered with 45 chromosomes,...
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- An inversion heterozygote has the following inverted chromosome. (A diploid is represented in each case, with the two homologues of the chromosome in question.) [Note: "o" = centromere] A B C DE F G HI J fedcbghij (i) Draw the alignment of these chromosomes during meiosis. (ii) Draw the products of a single crossover between homologous genes C and D in the inversion. (iii) Considering the position of the centromere, what is the sort of inversion called?arrow_forwardAn initial crossover event will occur between A and B, as indicated in the corresponding image. After this initial event occurs, a second cross over event occurs (not illustrated) involving the products of the first crossover event. Given the chromosome organization below, which two chromatids of the bivalent were involved and between which genes did the second crossover event occur to produce the indicated chromosomes? a. A B c, A b c, a B C, and a b C b. A B C, A B C, a b c, and a b c (return to the original crossover depicted in the image, and then determine how the second crossover event produced this arrangementarrow_forwardWhat is a balanced chromosomal rearrangement?arrow_forward
- The karyotype of a young girl who is affected with Down syndrome revealed that she has 46 chromosomes. Her phenotypically normal older brother's karyotype revealed that he has 45 chromosomes. (a) Propose an explanantion for the chromosome number in both children (b) What would you expect the chromosome number of the parents of these two children?arrow_forwardwhat is the significance of chromosomal aberration? what are the different types of chromosomal abberations based on the structure and number of chromosomes? give examples for each. what environmental factors may increase in the incidence of chromosomal aberrations?arrow_forwardA chromosome of genotype C D recombines with a homolog of genotype c d during meiosis when Spo11 produces a double-strand break between genes C and D. If anticrossover helicase disentangles the invading strand, the likely outcome would be A) two C D and two c d gametes. B) two C d and two c D gametes. C) one C D, one C d, one c D, and one c d gamete. D) four C D gametes. E) four c d gametesarrow_forward
- Kuliev and Verlinsky (2004) state that there was a relatively high number of separation errors at meiosis I. In these cases the centromere underwent a premature division, occurring at meiosis I rather than meiosis II. Regarding chromosome 21, what would you expect to be the chromosome 21 complement in the secondary oocyte in which you saw a single chromatid (monad) for chromosome 21 in the first polar body? If this secondary oocyte was involved in fertilization, what would be the expected consequences?arrow_forwardIn rice, male sterility is controlled by maternal cytoplasmic elements. This phenotype renders the male part of rice plants (i.e. the stamen) unable to produce fertile pollen; the female parts, however, remain receptive to pollination by pollen from male fertile rice plants. However, the presence of a nuclear fertility restorer gene F restores fertility to male-sterile lines. Give the result(s) of the cross and explain the phenotype of the offspring.arrow_forwardCould you have generated a chromosome map from the F2 progeny in cross 1 (assuming you crossed F1 males and females to each other to generate the F2)? What is the advantage of using cross 2 instead?arrow_forward
- A diploid individual is heterozygous for a chromosome rearrangement. The original chromosome and its rearranged homolog have the following segments, where ∙ represents a centromere: A B ∙ C D E F G A B ∙ C F E D G While paired in prophase I, a single crossing-over occurs between segment E and segment D of the paired chromosomes. Describe the unusual crossing-over structure that forms as a result.What gamete types will result from crossing over when meiosis is complete? please asaparrow_forwardIn corn, the genes v (virescent seedlings), pr (red aleurone), and bm (brown midrib) are all on chromosome 5, but not necessarily in the order given. The cross: v+ pr bm/ v pr+ bm+ with v pr bm/ v pr bm produces 1000 progeny with the following phenotypes: v+ pr bm 226 v pr+ bm+ 229 v+ pr bm+ 153 v pr+ bm 185 v+ pr+ bm 59 v pr bm+ 71 v+ pr+ bm+ 36 v pr bm 41 What is the gene order, and the (b) genetic map of these three genes?arrow_forwardFemales heterozygous for the recessive second chromosome mutations px, sp, and cn are mated to a male homozygous for all three mutations. The offspring are as follows: Must show all work 1.) What gene is in the middle? and what are the map distances between the genes in centimorgans? 2.) What is the interference?arrow_forward
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