Concepts of Genetics (12th Edition)
12th Edition
ISBN: 9780134604718
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino, Darrell Killian
Publisher: PEARSON
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Chapter 8, Problem 27ESP
A boy with Klinefelter syndrome (47,XXY) is born to a mother who is phenotypically normal and a father who has the X-linked skin condition called anhidrotic ectodermal dysplasia. The mother’s skin is completely normal with no signs of the skin abnormality. In contrast, her son has patches of normal skin and patches of abnormal skin.
- (a) Which parent contributed the abnormal gamete?
- (b) Using the appropriate genetic terminology, describe the meiotic mistake that occurred. Be sure to indicate in which division the mistake occurred.
- (c) Using the appropriate genetic terminology, explain the son’s skin
phenotype .
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A boy with Klinefelter syndrome (47,XXY) is born to a motherwho is phenotypically normal and a father who has the X-linkedskin condition called anhidrotic ectodermal dysplasia. The mother’sskin is completely normal with no signs of the skin abnormality.In contrast, her son has patches of normal skin and patchesof abnormal skin.
Question: Which parent contributed the abnormal gamete?
The autosomal (not X-linked) gene for brachydactyly, short fingers, is dominant to normal finger length. Assume that a female with brachydactyly in the heterozygous condition is married to a man with normal fingers. What is the probability that(a) their first child will have brachydactyly?(b) their first two children will have brachydactyly?(c) their first child will be a brachydactylous girl?
A boy with Klinefelter syndrome (47,XXY) is born to a mother who is phenotypically normal and a father who has the X- linked skin condition called anhidrotic ectodermal dysplasia. The boy has patches of normal skin and patches of abnormal skin. Which of the following statemnets likely explains these observations?
The father contributed the extra X chromosome in the son as a result of a non-disjunction in meiosis I during spermatogenesis.
The mother contributed the extra X chromosome in the son as a result of a non-disjunction in meiosis II during oogenesis.
The mother contributed the extra X chromosome in the son as a result of a non-disjunction in meiosis I during oogenesis.
The father contributed the extra X chromosome in the son as a result of a non-disjunction in meiosis II during spermatogenesis.
Either parent could have contributed to the extra X chromosome in the son as a results of disjunction in either meiosis I or meiosis II during…
Chapter 8 Solutions
Concepts of Genetics (12th Edition)
Ch. 8 - A human female with Turner syndrome (47, X) also...Ch. 8 - When two plants belonging to the same genus but...Ch. 8 - What is the effect of a rare double crossover (a)...Ch. 8 - Controlling the overgrowth of invasive aquatic...Ch. 8 - Controlling the overgrowth of invasive aquatic...Ch. 8 - Controlling the overgrowth of invasive aquatic...Ch. 8 - HOW DO WE KNOW? In this chapter, we have focused...Ch. 8 - Review the Chapter Concepts list on page 171....Ch. 8 - Define these pairs of terms, and distinguish...Ch. 8 - For a species with a diploid number of 18,...
Ch. 8 - What evidence suggests that Down syndrome is more...Ch. 8 - What evidence indicates that humans with aneuploid...Ch. 8 - Contrast the fertility of an allotetraploid with...Ch. 8 - Describe the origin of cultivated American cotton.Ch. 8 - Predict how the synaptic configurations of...Ch. 8 - Inversions are said to suppress crossing over. Is...Ch. 8 - Contrast the genetic composition of gametes...Ch. 8 - Human adult hemoglobin is a tetramer containing...Ch. 8 - Discuss Ohnos hypothesis on the role of gene...Ch. 8 - What roles have inversions and translocations...Ch. 8 - The primrose, Primula kewensis, has 36 chromosomes...Ch. 8 - Certain varieties of chrysanthemums contain 18,...Ch. 8 - Drosophila may be monosomic for chromosome 4, yet...Ch. 8 - Mendelian ratios are modified in crosses involving...Ch. 8 - Having correctly established the F2 ratio in...Ch. 8 - The mutations called bobbed in Drosophila result...Ch. 8 - The outcome of a single crossover between...Ch. 8 - A couple planning their family are aware that...Ch. 8 - In a cross in Drosophila, a female heterozygous...Ch. 8 - A woman who sought genetic counseling is found to...Ch. 8 - Prob. 25ESPCh. 8 - In a recent cytogenetic study on 1021 cases of...Ch. 8 - A boy with Klinefelter syndrome (47,XXY) is born...Ch. 8 - Prob. 28ESPCh. 8 - A 3-year-old child exhibited some early indication...Ch. 8 - A normal female is discovered with 45 chromosomes,...
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Hemophilia is an X-linked recessive disease. A hemophilic man marries a woman who is not a carrier of the disease. (a) Draw a Punnett square showing the genotypes of their children. (b) What are the chances that their daughters will be carriers of the disease? (c) What percentage of their children are likely to have the disease?arrow_forwardTwo brothers have thick hair that grows over their faces and most of their bodies. This human disorder, called Ambras Syndrome, shows x-linked dominant inheritance. The mother of the boys is also affected by Ambras Syndrome, although her excessive hair growth occurs in various, scattered patches on her skin rather than a continuous coverage like her sons. What is the most likely explanation for the patchy expression of hairlessness on the mother's skin? (2-3 sentences)arrow_forwardA human female with Turner syndrome (45,X) also expresses the X-linked trait hemophilia, as did her father. Which of her parents underwent nondisjunction during meiosis, giving rise to the gamete responsible for the syndrome?arrow_forward
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- Neurofibromatosis-1 (NF1) is an autosomal dominant disorder where tumours form in the base layer of the skin or in nerve tissues. What is the probability that individuals II-1 and II-2 will have a genetic son with NF1? Find the image attached.arrow_forwardWhy doesn’t the father (II-1) have the disease breast cancer? What is the formal name for an individual having the gene but not showing the trait?arrow_forwardMr. and Mrs. Smith, both 40 years of age, are healthy with no knowngenetic conditions. Their newborn child has Down syndrome (trisomy 21).Explain the events that caused this condition.arrow_forward
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