Biochemistry: Concepts and Connections (2nd Edition)
Biochemistry: Concepts and Connections (2nd Edition)
2nd Edition
ISBN: 9780134641621
Author: Dean R. Appling, Spencer J. Anthony-Cahill, Christopher K. Mathews
Publisher: PEARSON
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Chapter 7, Problem 3P

Antibodies raised against a macromolecular antigen (e.g, a protein) generally form an antigen-Ab precipitate when mixed with the antigen at roughly equimolar concentrations. However, little to no precipitate forms if the antibody is added in great excess (e.g., 20-fold molar excess) compared to the target antigen. Explain this observation.

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