8th Edition

ISBN: 9781305268920

Author: Bernard Rosner

Publisher: Cengage Learning

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Textbook Question

Chapter 7, Problem 15P

Suppose the incidence rate of myocardial infarction (Ml) was 5 per 1000 among 45- to 54-year-old men in 2000. To look at changes in incidence over time, 5000 men in this age group were followed for 1 year starting in 2010. Fifteen new cases of Ml were found.

Suppose we eventually plan to accumulate 50 Ml cases during the period 2010-2015. Assume that the 24-hour case-fatality rate is truly 20% during this period. How much power would such a study have in distinguishing between case-fatality rates in 2000 and 2010-2015 if a two-sided test with significance level .05 is planned?

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Chapter 7, Problem 14P

Chapter 7, Problem 16P

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Suppose that the incidence rate pf myocardial infraction (MI) was 5 per 100 among 45 - 50 year old men in 2000. To look at changes in incidence over time, 5000 men in this age groups were followed for 1 year starting in 2010. Twenty new cases of MI were found. Suppose we eventually plan to accumulate 50 MI cases during the period 2010-2015. Suppose that 20% of the patients with MI in 2000 died within 24 hours. This proportion is called the 24 hour case fatality rate. A test is performed to see if the true proportion of 24 hour case fatality rate differs from 20%, with significance level of 0.01. Assume that the 24-hour case fatality rate is truly 25% during the period. how large a sample is needed to achieve 92% power?

Suppose the incidence rate of myocardial infarction (MI)was 5 per 1000 among 45- to 54-year-old men in 2000.To look at changes in incidence over time, 5000 men in thisage group were followed for 1 year starting in 2010. Fifteennew cases of MI were found. Suppose that 25% of patients with MI in 2000 died within24 hours. This proportion is called the 24-hour case-fatalityrate. >How large a sample is needed in Problem 7.15 toachieve 90% power?

Suppose the test for Corona is 99% accurate in both directions and 0.3% of the population is Corona positive. If someone tests positive, what is the approximate percentage that they actually are suffering from corona?

Chapter 7 Solutions

Fundamentals of Biostatistics

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Solution Summary: The author estimates the power to distinguish between case-fatality rates in 2000 and 2010–2015. The power is 0.1079.

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