Organic Chemistry (8th Edition)
8th Edition
ISBN: 9780134042282
Author: Paula Yurkanis Bruice
Publisher: PEARSON
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Textbook Question
Chapter 4, Problem 80P
Citrate synthase, one of the enzymes in the series of enzyme-catalyzed reactions known as the citric acid cycle (Section 24.9), catalyzes the synthesis of citric acid from oxaloacetic acid and acetyl-CoA. If the synthesis is carried out with acetyl-CoA that contains radioactive carbon (14C) in the indicated position (Section 1.1), the isomer shown here is obtained.
- a. Which stereoisomer of citric acid is synthesized: R or S?
- b. If the acetyl-CoA used in the synthesis contains 12C instead of 14C, will the product of the reaction be chiral or achiral?
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Chapter 4 Solutions
Organic Chemistry (8th Edition)
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