Biochemistry
Biochemistry
9th Edition
ISBN: 9781319114671
Author: Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher: W. H. Freeman
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Chapter 33, Problem 11P
Interpretation Introduction

Interpretation:

The effect of the addition of IRE to the 5’ end and 3’ end of mRNA should be determined.

Concept introduction:

IRE (iron response element) is a conserved stem-loop structure which is bound to IRP (iron response proteins). The untranslated regions (UTRs) of mRNAs are bound to IRE. The products of UTRs are involved in iron metabolism. For instance, the 5’ end of mRNA of ferritin contains an IRE group.

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